Browsing Artículos by Author "Bhanot, Sanjay"

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      Methionine adenosyltransferase 1a antisense oligonucleotides activate the liver-brown adipose tissue axis preventing obesity and associated hepatosteatosis 

      Saenz de Urturi Indart, Diego; Buqué García, Xabier ORCID; Porteiro, Begoña; Folgueira, Cintia; Mora, Alfonso; Delgado, Teresa C.; Prieto Fernández, Endika; Olaizola Rebe, Paula; Gómez Santos, Beatriz; Apodaka Biguri, Maider; González Romero, Francisco; Nieva Zuluaga, Ane; Ruiz de Gauna Madariaga, Mikel; Goikoetxea Usandizaga, Naroa; García Rodríguez, Juan Luis; Gutiérrez de Juan, Virginia; Aurrekoetxea Galindo, Igor ORCID; Montalvo Romeral, Valle; Novoa, Eva; Martín Guerrero, Idoia; Varela Rey, Marta; Bhanot, Sanjay; Lee, Richard; Bañales Asurmendi, Jesús María ORCID; Syn, Wing-Kin; Sabio, Guadalupe; Martínez Chantar, María Luz ORCID; Nogueiras Pozo, Rubén; Aspichueta Celaá, Patricia (Nature, 2022)
      Altered methionine metabolism is associated with weight gain in obesity. The methionine adenosyltransferase (MAT), catalyzing the first reaction of the methionine cycle, plays an important role regulating lipid metabolism. ...