Browsing Artículos by Author "Borca, Manuel V."
Now showing items 1-4 of 4
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Classical Swine Fever Virus p7 Protein Interacts with Host Protein CAMLG and Regulates Calcium Permeability at the Endoplasmic Reticulum
Gladue, Douglas P.; Largo Pereda, Eneko; Holinka, Lauren G.; Ramirez-Medina, Elizabeth; Vuono, Elizabeth A.; Berggren, Keith A.; Risatti, Guillermo R.; Nieva Escandón, José Luis; Borca, Manuel V. (MDPI, 2018-09)We have previously shown that Classical Swine Fever Virus (CSFV) p7 is an essential nonstructural protein with a viroporin activity, a critical function in the progression of virus infection. We also identified p7 domains ... -
Classical Swine Fever Virus p7 Protein Is a Viroporin Involved in Virulence in Swine
Gladue, Douglas P.; Holinka, Lauren G.; Largo Pereda, Eneko; Fernández Sainz, Ignacio; Carrillo, Consuelo; O’Donnell, Vivian; Baker-Branstetter, Ryan; Lu, Zhiqiang; Ambroggio, Xavier; Risatti, Guillermo R.; Nieva Escandón, José Luis; Borca, Manuel V. (American Society of Microbiology, 2012-06-15)The nonstructural protein p7 of classical swine fever virus (CSFV) is a small hydrophobic polypeptide with an apparent molecular mass of 6 to 7 kDa. The protein contains two hydrophobic stretches of amino acids interrupted ... -
Effect of specific amino acid substitutions in the putative fusion peptide of structural glycoprotein E2 on Classical Swine Fever Virus replication
Fernández Sainz, Ignacio; Largo Pereda, Eneko; Gladue, Douglas P.; O’Donnell, Vivian; Holinka, Lauren G.; Carey, L.B.; Lu, X; Nieva Escandón, José Luis; Borca, Manuel V. (Elsevier, 2014-05)E2, along with Erns and E1, is an envelope glycoprotein of Classical Swine Fever Virus (CSFV). E2 is involved in several virus functions: cell attachment, host range susceptibility and virulence in natural hosts. Here we ... -
Pore-forming activity of pestivirus p7 in a minimal model system supports genus-specific viroporin function
Largo Pereda, Eneko; Gladue, Douglas P.; Huarte Arrayago, Nerea; Borca, Manuel V.; Nieva Escandón, José Luis (Elsevier, 2013-11-02)...