Browsing Artículos by Author "Borrego, Francisco"
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Identification of a panel of serum protein markers in early stage of sepsis and its validation in a cohort of patients
Garcia-Obregon, Susana; Azkargorta, Mikel; Seijas, Iratxe; Pilar-Orive, Javier; Borrego, Francisco; Elortza, Felix; Boyano López, María Dolores ; Astigarraga Aguirre, María Iciar (Elsevier, 2018-08)Background: Sepsis is a life-threatening illness with a challenging diagnosis. Current serum biomarkers are not sensitive enough for diagnosis. With the aim of finding proteins associated with sepsis, serum protein profile ... -
Long Interleukin-22 Binding Protein Isoform-1 Is an Intracellular Activator of the Unfolded Protein Response
Gómez Fernández, Paloma; Urtasun Arricaberri, Andoni; Paton, Adrienne W.; Paton, James C.; Borrego, Francisco; Dersh, Devin; Argon, Yair; Alloza Moral, Iraide; Vandenbroeck, Koen (Frontiers Media, 2018-12-14)The human IL22RA2 gene co-produces three protein isoforms in dendritic cells [IL-22 binding protein isoform-1 (IL-22BPi1), IL-22BPi2, and IL-22BPi3]. Two of these, IL-22BPi2 and IL-22BPi3, are capable of neutralizing the ...