Browsing Artículos by Author "Cahais, Vincent"
Now showing items 1-3 of 3
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Epigenetic remodelling of enhancers in response to estrogen deprivation and re-stimulation
Sklias, Athena; Halaburkova, Andrea; Vanzan, Ludovica; Fernández Jiménez, Nora ; Cuenin, Cyrille; Bouaoun, Liacine; Cahais, Vincent; Ythier, Victor; Salle, Aurelie; Renard, Claire; Durand, Geoffroy; Le Calvez Kelm, Florence; Khoueiry, Rita; Murr, Rabih; Herceg, Zdenko (Oxford University Press, 2021-09-27)Estrogen hormones are implicated in a majority of breast cancers and estrogen receptor alpha (ER), the main nuclear factor mediating estrogen signaling, orchestrates a complex molecular circuitry that is not yet fully ... -
Human mitochondrial DNA is extensively methylated in a non-CpG context
Patil, Vibha; Cuenin, Cyrille; Chung, Felicia; Rodríguez Aguilera, Jesús R.; Fernández Jiménez, Nora ; Romero Garmendia, Irati; Bilbao Catalá, José Ramón ; Cahais, Vincent; Rothwell, Joseph; Herceg, Zdenko (Oxford University Press, 2019-09-06)Mitochondrial dysfunction plays critical roles in cancer development and related therapeutic response; however, exact molecular mechanisms remain unclear. Recently, alongside the discovery of mitochondrial-specific DNA ... -
The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region
Fernández Jiménez, Nora ; García Etxebarria, Koldo; Plaza Izurieta, Leticia; Romero Garmendia, Irati; Jauregi Miguel, Amaia; Legarda, Maria; Ecsedi, Szilvia; Castellanos Rubio, Ainara; Cahais, Vincent; Cuenin, Cyrille; Degli Esposti, Davide; Irastorza Terradillos, Iñaki Xarles ; Hernandez-Vargas, Hector; Herceg, Zdenko; Bilbao Catalá, José Ramón (Nature Publishing, 2019-02-04)The Human Leucocyte Antigen (HLA) locus and other DNA sequence variants identified in Genome-Wide Association (GWA) studies explain around 50% of the heritability of celiac disease (CD). However, the pathogenesis of CD ...