Browsing Artículos by Author "Dalla Torre, Gabriele"

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      Aluminum's preferential binding site in proteins: sidechain of amino acids versus backbone interactions 

      Mujika, Jon I.; Dalla Torre, Gabriele; Formoso Estensoro, Elena; Grande-Aztatzi, Rafael; Grabowski, Slawomir J.; Exley, Christopher; Lopez, Xabier (Elsevier, 2017-11-11)
      The interaction of aluminum ion Al(III) with polypeptides is a subject of paramount importance, since it is a central feature to understand its deleterious effects in biological systems. Various drastic effects have been ...
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      Thymosin β4 Is an Endogenous Iron Chelator and Molecular Switcher of Ferroptosis 

      Lachowicz, Joanna I.; Pichiri, Giusi; Piludu, Marco; Fais, Sara; Orrù, Germano; Congiu, Terenzio; Piras, Monica; Faa, Gavino; Fanni, Daniela; Dalla Torre, Gabriele; López Pestaña, José Javier; Chandra, Kousik; Szczepski, Kacper; Jaremko, Lukasz; Ghosh, Mitra; Emwas, Abdul-Hamid; Castagnola, Massimo; Jaremko, Mariusz; Hannappel, Ewald; Coni, Pierpaolo (MDPI, 2022-01-04)
      Thymosin β4 (Tβ4) was extracted forty years agofrom calf thymus. Since then, it has been identified as a G-actin binding protein involved in blood clotting, tissue regeneration, angiogenesis, and anti-inflammatory processes. ...
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      Tuning the Affinity of Catechols and Salicylic Acids towards Al(III): Characterization of Al-Chelator Interactions 

      Dalla Torre, Gabriele; Mujika, Jon I.; Formoso, Elena; Matito, Eduard; Ramos, Maria J.; Lopez, Xabier (2018-06-11)
      Due to aluminum's controversial role in neurotoxicity, the goal of chelation therapy, the removal of the toxic metal ion or attenuation of its toxicity by transforming it into less toxic compounds, has attracted considerable ...