Browsing Artículos by Author "Espona Noguera, Albert"
Now showing items 1-6 of 6
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3D Printed Porous Polyamide Macrocapsule Combined with Alginate Microcapsules for Safer Cell-Based Therapies
Sáenz del Burgo Martínez, Laura ; Ciriza Astrain, Jesús; Espona Noguera, Albert; Xavier, Illa; Cabruja Casas, Enric; Orive Arroyo, Gorka; Hernández Martín, Rosa María ; Villa, Rosa; Pedraz Muñoz, José Luis ; Álvarez, Mar (Nature Publishing Group, 2018-05-31)Cell microencapsulation is an attractive strategy for cell-based therapies that allows the implantation of genetically engineered cells and the continuous delivery of de novo produced therapeutic products. However, the ... -
BSA- and Elastin-Coated GO, but Not Collagen-Coated GO, Enhance the Biological Performance of Alginate Hydrogels
Raslan, Ahmed; Sáenz del Burgo Martínez, Laura ; Espona Noguera, Albert; Ochoa de Retana Mendibil, Ana María ; Sanjuán, María Luisa; Cañibano Hernández, Alberto; Gálvez Martín, Patricia; Ciriza Astrain, Jesús; Pedraz Muñoz, José Luis (MDPI, 2020-06-11)The use of embedded cells within alginate matrices is a developing technique with great clinical applications in cell-based therapies. However, one feature that needs additional investigation is the improvement of ... -
Characterization of encapsulated porcine cardiosphere-derived cells embedded in 3D alginate matrices
Ziania, Kaoutar; Espona Noguera, Albert; Crisóstomo, Verónica; Casado, Javier G.; Sánchez Margallo, Francisco Miguel; Sáenz del Burgo Martínez, Laura ; Ciriza Astrain, Jesús; Pedraz Muñoz, José Luis (Elsevier, 2021-04-15)Myocardial infarction is caused by an interruption of coronary blood flow, leading to one of the main death causes worldwide. Current therapeutic approaches are palliative and not able to solve the loss of cardiac tissue. ... -
Intrapericardial Delivery of APA-Microcapsules as Promising Stem Cell Therapy Carriers in an Experimental Acute Myocardial Infarction Model
Báez Díaz, Claudia; Blanco Blázquez, Virginia; Sánchez-Margallo, Francisco Miguel; López, Esther; Martín, Helena; Espona Noguera, Albert; Casado, Javier G.; Ciriza, Jesús; Pedraz Muñoz, José Luis ; Crisóstomo, Verónica (MDPI, 2021-11-01)The administration of cardiosphere-derived cells (CDCs) after acute myocardial infarction (AMI) is very promising. CDC encapsulation in alginate-poly-l-lysine-alginate (APA) could increase cell survival and adherence. The ... -
Review of Advanced Hydrogel-Based Cell Encapsulation Systems for Insulin Delivery in Type 1 Diabetes Mellitus
Espona Noguera, Albert; Ciriza Astrain, Jesús; Cañibano Hernández, Alberto; Orive Arroyo, Gorka; Hernández Martín, Rosa María ; Sáenz del Burgo Martínez, Laura ; Pedraz Muñoz, José Luis (MDPI, 2019-11-12)Type 1 Diabetes Mellitus (T1DM) is characterized by the autoimmune destruction of beta-cells in the pancreatic islets. In this regard, islet transplantation aims for the replacement of the damaged beta-cells through minimally ... -
Type 1 Diabetes Mellitus reversal via implantation of magnetically purified microencapsulated pseudoislets
Espona Noguera, Albert; Etxebarria Elezgarai, Jaione ; Sáenz del Burgo Martínez, Laura ; Cañibano Hernández, Alberto; Gurruchaga Iribar, Haritz ; Blanco, Francisco Javier; Orive Arroyo, Gorka; Hernández Martín, Rosa María ; Benito López, Fernando ; Ciriza Astrain, Jesús; Basabe Desmonts, Lourdes ; Pedraz Muñoz, José Luis (Elsevier, 2019-02-10)Microencapsulation of pancreatic islets for the treatment of Type I Diabetes Mellitus (T1DM) generates a high quantity of empty microcapsules, resulting in high therapeutic graft volumes that can enhance the host’s immune ...