Now showing items 1-6 of 6

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      3D Printed Porous Polyamide Macrocapsule Combined with Alginate Microcapsules for Safer Cell-Based Therapies 

      Sáenz del Burgo Martínez, Laura ORCID; Ciriza Astrain, Jesús; Espona Noguera, Albert; Xavier, Illa; Cabruja Casas, Enric; Orive Arroyo, Gorka; Hernández Martín, Rosa María ORCID; Villa, Rosa; Pedraz Muñoz, José Luis ORCID; Álvarez, Mar (Nature Publishing Group, 2018-05-31)
      Cell microencapsulation is an attractive strategy for cell-based therapies that allows the implantation of genetically engineered cells and the continuous delivery of de novo produced therapeutic products. However, the ...
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      BSA- and Elastin-Coated GO, but Not Collagen-Coated GO, Enhance the Biological Performance of Alginate Hydrogels 

      Raslan, Ahmed; Sáenz del Burgo Martínez, Laura ORCID; Espona Noguera, Albert; Ochoa de Retana Mendibil, Ana María ORCID; Sanjuán, María Luisa; Cañibano Hernández, Alberto; Gálvez Martín, Patricia; Ciriza Astrain, Jesús; Pedraz Muñoz, José Luis ORCID (MDPI, 2020-06-11)
      The use of embedded cells within alginate matrices is a developing technique with great clinical applications in cell-based therapies. However, one feature that needs additional investigation is the improvement of ...
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      Characterization of encapsulated porcine cardiosphere-derived cells embedded in 3D alginate matrices 

      Ziania, Kaoutar; Espona Noguera, Albert; Crisóstomo, Verónica; Casado, Javier G.; Sánchez Margallo, Francisco Miguel; Sáenz del Burgo Martínez, Laura ORCID; Ciriza Astrain, Jesús; Pedraz Muñoz, José Luis ORCID (Elsevier, 2021-04-15)
      Myocardial infarction is caused by an interruption of coronary blood flow, leading to one of the main death causes worldwide. Current therapeutic approaches are palliative and not able to solve the loss of cardiac tissue. ...
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      Intrapericardial Delivery of APA-Microcapsules as Promising Stem Cell Therapy Carriers in an Experimental Acute Myocardial Infarction Model 

      Báez Díaz, Claudia; Blanco Blázquez, Virginia; Sánchez-Margallo, Francisco Miguel; López, Esther; Martín, Helena; Espona Noguera, Albert; Casado, Javier G.; Ciriza, Jesús; Pedraz Muñoz, José Luis ORCID; Crisóstomo, Verónica (MDPI, 2021-11-01)
      The administration of cardiosphere-derived cells (CDCs) after acute myocardial infarction (AMI) is very promising. CDC encapsulation in alginate-poly-l-lysine-alginate (APA) could increase cell survival and adherence. The ...
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      Review of Advanced Hydrogel-Based Cell Encapsulation Systems for Insulin Delivery in Type 1 Diabetes Mellitus 

      Espona Noguera, Albert; Ciriza Astrain, Jesús; Cañibano Hernández, Alberto; Orive Arroyo, Gorka; Hernández Martín, Rosa María ORCID; Sáenz del Burgo Martínez, Laura ORCID; Pedraz Muñoz, José Luis ORCID (MDPI, 2019-11-12)
      Type 1 Diabetes Mellitus (T1DM) is characterized by the autoimmune destruction of beta-cells in the pancreatic islets. In this regard, islet transplantation aims for the replacement of the damaged beta-cells through minimally ...
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      Type 1 Diabetes Mellitus reversal via implantation of magnetically purified microencapsulated pseudoislets 

      Espona Noguera, Albert; Etxebarria Elezgarai, Jaione ORCID; Sáenz del Burgo Martínez, Laura ORCID; Cañibano Hernández, Alberto; Gurruchaga Iribar, Haritz ORCID; Blanco, Francisco Javier; Orive Arroyo, Gorka; Hernández Martín, Rosa María ORCID; Benito López, Fernando ORCID; Ciriza Astrain, Jesús; Basabe Desmonts, Lourdes ORCID; Pedraz Muñoz, José Luis ORCID (Elsevier, 2019-02-10)
      Microencapsulation of pancreatic islets for the treatment of Type I Diabetes Mellitus (T1DM) generates a high quantity of empty microcapsules, resulting in high therapeutic graft volumes that can enhance the host’s immune ...