Browsing Artículos by Author "Walker, Brian"
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The conserved helix C region in the superfamily of interferon-gamma /interleukin-10-related cytokines corresponds to a high-affinity binding site for the HSP70 chaperone DnaK.
Vandenbroeck, Koen; Alloza Moral, Iraide; Brehmer, Dirk; Billiau, Alfons; Proost, Paul; McFerran, Neil; Rüdiger, Stefan; Walker, Brian (Elsevier, 2002-07-12)HSP70 chaperones mediate protein folding by ATP-dependent interaction with short linear peptide segments that are exposed on unfolded proteins. The mode of action of the Escherichia coli homolog DnaK is representative of ...