Now showing items 1-3 of 3

    • Thumbnail

      Accumulated Bending Energy Elicits Neutral Sphingomyelinase Activity in Human Red Blood Cells 

      López Jiménez, David ORCID; Egibo-Gabas, Meritxell; Lopez-Montero, Ivan; Busto Gamero, Jon V.; Casas, Josefina; Garnier, Marie; Monroy, Francisco; Larijani, Banafshe; Goñi Urcelay, Félix María ORCID; Alonso Izquierdo, Alicia ORCID (Elservier, 2012-05-02)
      [EN] We propose that accumulated membrane bending energy elicits a neutral sphingomyelinase (SMase) activity in human erythrocytes. Membrane bending was achieved by osmotic or chemical processes, and SMase activity was ...
    • Thumbnail

      Integration Through Separation - The Role of Lateral Membrane Segregation in Nutrient Uptake 

      Busto Gamero, Jon V.; Wedlich Soeldner, Roland (Frontiers Media, 2019-06-25)
      Nutrient transporters are prominent and ubiquitous components of the plasma membrane in all cell types. Their expression and regulation are tightly linked to the cells' needs. Environmental factors such as nutrient starvation ...
    • Thumbnail

      Pb(II) Induces Scramblase Activation and Ceramide-Domain Generation in Red Blood Cells 

      Ahyayauch, Hasna; García Arribas, Aritz ORCID; Sot, Jesús; González Ramírez, Emilio José; Busto Gamero, Jon V.; Gutiérrez Monasterio, Bingen ORCID; Jiménez Rojo, Noemi; Contreras Gómez, Xabier ORCID; Rendón Ramírez, Adela; Martín Plágaro, César Augusto; Alonso Izquierdo, Alicia ORCID; Goñi Urcelay, Félix María ORCID (Nature Publishing, 2018-05-10)
      The mechanisms of Pb(II) toxicity have been studied in human red blood cells using confocal microscopy, immunolabeling, fluorescence-activated cell sorting and atomic force microscopy. The process follows a sequence of ...