Now showing items 1-1 of 1

    • Thumbnail

      The methylome of the celiac intestinal epithelium harbours genotype-independent alterations in the HLA region 

      Fernández Jiménez, Nora ORCID; García Etxebarria, Koldo; Plaza Izurieta, Leticia; Romero Garmendia, Irati; Jauregi Miguel, Amaia; Legarda, Maria; Ecsedi, Szilvia; Castellanos Rubio, Ainara; Cahais, Vincent; Cuenin, Cyrille; Degli Esposti, Davide; Irastorza Terradillos, Iñaki Xarles ORCID; Hernandez-Vargas, Hector; Herceg, Zdenko; Bilbao Catalá, José Ramón ORCID (Nature Publishing, 2019-02-04)
      The Human Leucocyte Antigen (HLA) locus and other DNA sequence variants identified in Genome-Wide Association (GWA) studies explain around 50% of the heritability of celiac disease (CD). However, the pathogenesis of CD ...