Browsing Artículos by Author "Lukas, John"

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      Application of a dual mechanistic approach to support bilastine dose selection for older adults 

      Kim, Chaejin; Lo Re, Valentina; Rodríguez, Mónica; Lukas, John; Leal, Nerea; Campo, Cristina; García- Bea, Aintzane; Suárez González, María Elena; Schmidt, Stephan; Vozmediano, Valvanera (Wiley, 2021-09)
      The objective of this study was to evaluate bilastine dosing recommendations in older adults and overcome the limitation of insufficient data from phase I studies in this underrepresented population. This was achieved by ...
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      Evaluation of Fentanyl Disposition and Effects in Newborn Piglets as an Experimental Model for Human Neonates 

      Rey Santano, María Carmen; Mielgo, Victoria; Valls Soler, Adolfo; Encinas Pérez, Esther; Lukas, John; Vozmediano, Valvanera; Suárez González, María Elena (Public Library Science, 2014-03-04)
      Background: Fentanyl is widely used off-label in NICU. Our aim was to investigate its cerebral, cardiovascular and pulmonary effects as well as pharmacokinetics in an experimental model for neonates. Methods: Fentanyl ...