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      Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams-Beuren syndrome 

      Navarro Romero, Alba; Galera López, Lorena; Ortíz Romero, Paula; Llorente Ovejero, Alberto; de los Reyes Ramírez, Lucía; Bengoetxea de Tena, Iker; García Elías, Anna; Mas-Stachurska, Aleksandra; Reixachs Solé, Marina; Pastor, Antoni; De la Torre, Rafael; Maldonado, Rafael; Benito, Begoña; Eyras, Eduardo; Rodríguez Puertas, Rafael ORCID; Campuzano, Victoria; Ozaita, Andres (eLife Sciences, 2022-10)
      Williams-Beuren syndrome (WBS) is a rare genetic multisystemic disorder characterized by mild-to-moderate intellectual disability and hypersocial phenotype, while the most life-threatening features are cardiovascular ...
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      Possible therapeutic doses of cannabinoid type 1 receptor antagonist reverses key alterations in fragile X syndrome mouse model 

      Gomis-González, María; Busquets-Garcia, Arnau; Matute Almau, Carlos José; Maldonado, Rafael; Mato Santos, Susana ORCID; Ozaita, Andres (MDPI, 2016-08)
      Fragile X syndrome (FXS) is the most common monogenetic cause of intellectual disability. The cognitive deficits in the mouse model for this disorder, the Fragile X Mental Retardation 1 (Fmr1) knockout (KO) mouse, have ...