BackBrowsing Artículos by Author "Rodríguez, Manuel S."
Now showing items 1-3 of 3
-
Analysis of SUMOylated proteins using SUMO-traps
Da Silva Ferrada, Elisa; Xolalpa, Wendy; Lang, Valerie; Aillet, Fabienne; Martín-Ruiz, Itziar; De la Cruz-Herrera, Carlos F.; Lopitz Otsoa, Fernando; Carracedo Pérez, Arkaitz
; Goldenberg, Seth J.; Rivas, Carmen; England, Patrick; Rodríguez, Manuel S. (Nature Publishing Group, 2013-04-22)
SUMO-modified proteins are recognized by SUMO interacting motifs (SIMs), thus triggering diverse cellular responses. Here SIMs were used to develop SUMO-traps to capture endogenous SUMOylated proteins. Our results show ... -
SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; Ávila, Matías A.; ; ; ; ; ; Martínez Chantar, María Luz (Elsevier, 2019-02)
BACKGROUND: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular ... -
Surface Expression and Subunit Specific Control of Steady Protein Levels by the Kv7.2 Helix A-B Linker
; ; ; ; Alaimo Campi, Alessandro; ; ; ; ; (Public Library of Science, 2013-10-24)
Kv7.2 and Kv7.3 are the main components of the neuronal voltage-dependent M-current, which is a subthreshold potassium conductance that exerts an important control on neuronal excitability. Despite their predominantly ...