Now showing items 1-3 of 3

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      Analysis of SUMOylated proteins using SUMO-traps 

      Da Silva Ferrada, Elisa; Xolalpa, Wendy; Lang, Valerie; Aillet, Fabienne; Martín-Ruiz, Itziar; De la Cruz-Herrera, Carlos F.; Lopitz Otsoa, Fernando; Carracedo Pérez, Arkaitz ORCID; Goldenberg, Seth J.; Rivas, Carmen; England, Patrick; Rodríguez, Manuel S. (Nature Publishing Group, 2013-04-22)
      SUMO-modified proteins are recognized by SUMO interacting motifs (SIMs), thus triggering diverse cellular responses. Here SIMs were used to develop SUMO-traps to capture endogenous SUMOylated proteins. Our results show ...
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      SUMOylation regulates LKB1 localization and its oncogenic activity in liver cancer 

      Zubiete Franco, Imanol; García-Rodríguez, Juan Luis; Lopitz Otsoa, Fernando; Serrano Maciá, Marina; Simón Espinosa, Jorge; Fernández Tussy, Pablo; Barbier Torres, Lucía; Fernández Ramos, David; Gutiérrez de Juan, Virginia; López de Davalillo, Sergio; Carlevaris, Onintza; Beguiristain Gómez, Adolfo; Villa, Erica; Calvisi, Diego; Martín Plágaro, César Augusto; Berra Ramírez, Miren Edurne; Aspichueta Celaá, Patricia; Beraza, Naiara; Varela Rey, Marta; Ávila, Matías A. ORCID; Rodríguez, Manuel S.; Mato, José M.; Díaz Moreno, Irene; Díaz Quintana, Antonio; Delgado, Teresa C.; Martínez Chantar, María Luz ORCID (Elsevier, 2019-02)
      BACKGROUND: Even though liver kinase B1 (LKB1) is usually described as a tumor suppressor in a wide variety of tissues, it has been shown that LKB1 aberrant expression is associated with bad prognosis in Hepatocellular ...
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      Surface Expression and Subunit Specific Control of Steady Protein Levels by the Kv7.2 Helix A-B Linker 

      Aivar, Paloma; Fernández-Orth, Juncal; Gomis Pérez, Carolina; Alberdi González, Araitz; Alaimo Campi, Alessandro ORCID; Rodríguez, Manuel S.; Giraldez, Teresa; Miranda, Pablo; Areso Goiricelaya, María Pilar; Villarroel Muñoz, Álvaro (Public Library of Science, 2013-10-24)
      Kv7.2 and Kv7.3 are the main components of the neuronal voltage-dependent M-current, which is a subthreshold potassium conductance that exerts an important control on neuronal excitability. Despite their predominantly ...