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Now showing items 101-110 of 114
Ocoxin as a complement to first line treatments in cancer
(Ivyspring International Publisher, 2021)
Chemotherapy and radiotherapy are the most frequent treatment for patients suffering from malignant progression of cancer. Even though new treatments are now being implemented, administration of these chemotherapeutic ...
Inhibition of the Human Hsc70 System by Small Ligands as a Potential Anticancer Approach
(MDPI, 2021-06-11)
Heat shock protein (Hsp) synthesis is upregulated in a wide range of cancers to provide the appropriate environment for tumor progression. The Hsp110 and Hsp70 families have been associated to cancer cell survival and ...
Lipid fingerprint-based histology accurately classifies nevus, primary melanoma, and metastatic melanoma samples
(Wiley, 2024-02)
Probably, the most important factor for the survival of a melanoma patient is early detection and precise diagnosis. Although in most cases these tasks are readily carried out by pathologists and dermatologists, there are ...
The new preservative-free ophthalmic formulation of bilastine 0.6% preserves the ocular surface epithelial integrity in a comparative in vitro study
(Nature, 2024)
Allergic conjunctivitis (AC) is the most common form of allergic eye disease and an increasingly prevalent condition. Topical eye drop treatments are the usual approach for managing AC, although their impact on the ocular ...
Systemic cellular migration: The forces driving the directed locomotion movement of cells
(Oxford University Press, 2024-04)
Directional motility is an essential property of cells. Despite its enormous relevance in many fundamental physiological and pathological
processes, how cells control their locomotion movements remains an unresolved ...
The role of Eudragit® as a component of hydrogel formulations for medical devices
(RSC, 2023)
Over the last decade, significant progress has been made in developing hydrogels as medical devices. By physically cross-linking pharmaceutically approved polymers into three-dimensional matrices, we can ensure their ...
The Prevention of Ischemia-Reperfusion Injury in Elderly Rats after Lower Limb Tourniquet Use
(MDPI, 2022-09-28)
Background: Lower limb ischemia-reperfusion injury (IRI-LL) is a common major complication of orthopedic surgery, especially in elderly patients. It has previously been demonstrated that folinic acid (FA) reduced IRI-LL ...
Furan-containing biobased polyurethane nanofibers: A new versatile and green support clickable via Diels-Alder reaction
(Elsevier, 2022-09)
A new biobased polyurethane formulation containing furan was synthesized and subsequently functionalized and de-functionalized via Diels-Alder and retro Diels-Alder reactions. Furan was inserted in the backbone polymer ...
Müller glial cells located in the peripheral retina are more susceptible to high pressure: implications for glaucoma
(BMC, 2024)
Background
Glaucoma, a progressive neurodegenerative disease, is a leading cause of irreversible vision loss worldwide. This study aims to elucidate the critical role of Müller glia (MG) in the context of retinal ganglion ...
URB447 Is Neuroprotective in Both Male and Female Rats after Neonatal Hypoxia–Ischemia and Enhances Neurogenesis in Females
(MDPI, 2024-01-28)
The need for new and effective treatments for neonates suffering from hypoxia–ischemia is urgent, as the only implemented therapy in clinics is therapeutic hypothermia, only effective in 50% of cases. Cannabinoids ...