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Multiple-Criteria Decision-Making Tool for Local Governments to Evaluate the Global and Local Sustainability of Transportation Systems in Urban Areas: Case Study
(ASCE, 2017-10-24)
Efficient management of urban transportation systems is a challenge for any local government that wishes to improve public wellbeing and comfort. With that end in mind, this paper proposes a tool for decision making and ...
MTHFR Polymorphisms In Childhood Acute lymphoblastic Leukemia: Influence On Methotrexate Therapy
(Dove Medical Press LTD, 2017)
Methotrexate (MTX) is an important component in the therapy used to treat childhood
acute lymphoblastic leukemia (ALL). Methylenetetrahydrofolate reductase (MTHFR) is a key
enzyme for MTX pharmacokinetics. Two single-nucleotide ...
Confirmation of involvement of new variants at CDKN2A/B in pediatric acute lymphoblastic leukemia susceptibility in the Spanish population
(Public Library Science, 2017-05-08)
The locus CDKN2A/B (9p21.3), which comprises the tumor suppressors genes CDKN2A and CDKN2B and the long noncoding RNA (lncRNA) known as ANRIL (or CDKN2B-AS), was associated with childhood acute lymphoblastic leukemia (ALL) ...
Animal-assisted psychotherapy for young people with behavioural problems in residential care
(Wiley, 2017)
The aim of this study was to evaluate the impact of an animal-assisted psychotherapy (AAP) programme on clinical symptoms, personal adjustment and adaptive skills in a group of adolescents in residential care who had ...
Genetics of ancestry-specific risk for relapse in acute lymphoblastic leukemia
(Springer Nature, 2017-01-18)
The causes of individual relapses in children with acute lymphoblastic leukemia (ALL) remain incompletely understood. We evaluated the contribution of germline genetic factors to relapse in 2225 children treated on Children's ...
MTHFR polymorphisms in childhood acute lymphoblastic leukemia: influence on methotrexate therapy
(Dove Medical Press, 2017-03-27)
Methotrexate (MTX) is an important component in the therapy used to treat childhood acute lymphoblastic leukemia ( ALL). Methylenetetrahydrofolate reductase ( MTHFR) is a key enzyme for MTX pharmacokinetics. Two single-nucleotide ...
Middle Pleistocene protein sequences from the rhinoceros genus Stephanorhinus and the phylogeny of extant and extinct Middle/Late Pleistocene Rhinocerotidae
(PeerJ Inc., 2017-03-14)
Ancient protein sequences are increasingly used to elucidate the
phylogenetic relationships between extinct and extant mammalian taxa. Here, we
apply these recent developments to Middle Pleistocene bone specimens of ...
Isotopic evidence for the reconstruction of diet and mobility during village formation in the Early Middle Ages: Las Gobas (Burgos, northern Spain)
(Springer, 2017-07-10)
Strontium, carbon, and nitrogen isotopes of human bone and tooth remains have been used to reconstruct residential mobility and diet of early medieval populations at Las Gobas from the sixth to eleventh centuries. Most ...