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Treatment with Allopurinol is Associated with Lower Risk of Acute Kidney Injury in Patients with Gout: A Retrospective Analysis of a Nested Cohort
(Springer, 2017-12)
Gout is characterized by recurrent episodes of acute inflammation of joint structures, called gout flares, and flares are commonly treated with nonsteroidal anti-inflammatory drugs (NSAIDs). The objective of the study was ...
Riparian plant litter quality increases with latitude
(Nature Publishing, 2017-09-05)
Plant litter represents a major basal resource in streams, where its decomposition is partly regulated by litter traits. Litter-trait variation may determine the latitudinal gradient in decomposition in streams, which is ...
Advances in Single-Chain Nanoparticles for Catalysis Applications
(MDPI, 2017-10-21)
Enzymes are the most efficient catalysts known for working in an aqueous environment near room temperature. The folding of individual polymer chains to functional single-chain nanoparticles (SCNPs) offers many opportunities ...
The Influence of Copolymer Composition on PLGA/nHA Scaffolds’ Cytotoxicity and In Vitro Degradation
(MDPI, 2017-07-06)
The influence of copolymer composition on Poly(Lactide-co-Glycolide)/nanohydroxyapatite (PLGA/nHA) composite scaffolds is studied in the context of bone tissue engineering and regenerative medicine. The composite scaffolds ...
Quantitative proteomic analysis of Parkin substrates in Drosophila neurons
(Biomed Central, 2017-04-11)
Background: Parkin (PARK2) is an E3 ubiquitin ligase that is commonly mutated in Familial Parkinson's Disease (PD). In cell culture models, Parkin is recruited to acutely depolarised mitochondria by PINK1. PINK1 activates ...
Expression and activity of angiotensin-regulating enzymes is associated with prognostic outcome in clear cell renal cell carcinoma patients
(Public Library Science, 2017-08-15)
The discovery of the intrarenal renin-angiotensin system (iRAS), which regulates angiogenesis, cell differentiation and proliferation, has opened new perspectives in the knowledge of kidney carcinogenesis. In this study ...
Agent-based middleware architecture for reconfigurable manufacturing systems
(Springer, 2017-09)
Modern manufacturing systems are expected to be flexible and efficient in order to cope with challenging market demands. Thus, they must be flexible enough as to meet changing requirements such as changes in production, ...
Advances in Fluorescent Single-Chain Nanoparticles
(MDPI, 2017-10-26)
Fluorophore molecules can be monitored by fluorescence spectroscopy and microscopy, which are highly useful and widely used techniques in cell biology, biochemistry, and medicine (e.g., biomarker analysis, immunoassays, ...
Lifestyle Patterns and Weight Status in Spanish Adults: The ANIBES Study
(MDPI, 2017-06)
Limited knowledge is available on lifestyle patterns in Spanish adults. We investigated dietary patterns and possible meaningful clustering of physical activity, sedentary behavior, sleep time, and smoking in Spanish adults ...
Dialogue with families: an opportunity to build the Decalogue of school sport in a participatory way
(MedCrave, 2017)
This paper presents the phases that families at three teaching centres went through to draw up their own behaviour decalogues in school sport competitions and deploy courses of action to improve the behaviour of families ...