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4D Printing: The Development of Responsive Materials Using 3D-Printing Technology
(MDPI, 2023-12-07)
Additive manufacturing, widely known as 3D printing, has revolutionized the production of biomaterials. While conventional 3D-printed structures are perceived as static, 4D printing introduces the ability to fabricate ...
Behavior And Ultrastructure Of Human Bone Marrow-Derived Mesenchymal Stem Cells Immobilized In Alginate-Poly-L-Lysine-Alginate Microcapsules
(Taylor & Francis, 2014-04-24)
Context: Human bone marrow mesenchymal stem cells (hBM-MSCs) show a great promise for the treatment of a variety of diseases. Despite the previous trials to encapsulate hBM-MSCs in alginate-poly-l-lysine-alginate (APA) ...
Antimicrobial susceptibility of Treponema pallidum subspecies pallidum: an in-vitro study
(Elsevier, 2023-10)
Background The increasing incidence of syphilis and the limitations of first-line treatment with penicillin, particularly in neurosyphilis, neonatal syphilis, and pregnancy, highlight the need to expand the therapeutic ...
Chemerin concentrations in infants born small for gestational age: correlations with triglycerides and parameters related to glucose homeostasis
(Springer, 2020-06-16)
[EN]Infants born small for gestational age (SGA) are known to have increased risk of developing several pathologies, including the
metabolic syndrome, when they grow up. It has been described that both the growth pattern ...
Human Hair Follicle-Derived Mesenchymal Stromal Cells from the Lower Dermal Sheath as a Competitive Alternative for Immunomodulation
(MDPI, 2022-01-24)
Mesenchymal stromal cells (MSCs) have unique immunomodulatory capacities. We investigated hair follicle-derived MSCs (HF-MSCs) from the dermal sheath, which are advantageous as an alternative source because of their ...
Gene delivery in the cornea: in vitro and ex vivo evaluation of solid lipid nanoparticle-based vectors
(Future Medicine, 2018-08-01)
Inflammation is a process that underlies sight-threatening ocular surface
diseases, and gene supplementation with the plasmid that encodes for interleukin-10 (p-
IL10) will allow the sustained de novo synthesis of the ...
Improvement of the monitoring and biosafety of encapsulated cells using the SFGNESTGL triple reporter system
(Elsevier, 2010-05-23)
Cell microencapsulation may represent a breakthrough to overcome problems associated with cell therapy. Advances in material biocompatibility and production protocols have put this field close to its clinical application. ...
Inactivation of encapsulated cells and their therapeutic effects by means of TGL triple-fusion reporter/biosafety gene
(Elsevier, 2012-11-19)
The immobilization of cells within alginate-poly-l-lysine-alginate (APA) microcapsules has been demonstrated to be an effective technology design for long term delivery of therapeutic products. Despite promising advances, ...
Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation
(MDPI, 2020-01-09)
Antimicrobial treatment in critically ill patients remains challenging. The aim of this study
was to develop a population pharmacokinetic model for linezolid in critically ill patients and to
evaluate the adequacy of ...
Novel advances in the design of three-dimensional bio-scaffolds to control cell fate: translation from 2D to 3D
(Elsevier, 2012-05-07)
Recreating the most critical aspects of the native extracellular matrix (ECM) is fundamental to understand and control the processes regulating cell fate and cell function. From the ill-defined complexity to the controlled ...