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Molecular Recognition of the Native HIV-1 MPER Revealed by STED Microscopy of Single Virions
(Springer, 2019-01-08)
Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, ...
Upregulated phospholipase D2 expression and activity is related to the metastatic properties of melanoma
(Spandidos, 2022-05)
[EN] The incidence rates of melanoma have increased steadily in recent decades and nearly 25% of the patients diagnosed with early-stage melanoma will eventually develop metastasis, for which there is currently no fully ...
High fat diet-induced non alcoholic fatty liver disease in rats is associated with hyperhomocysteinemia caused by down regulation of the transsulphuration pathway
(BioMed Central, 2011)
Background
Hyperhomocysteinemia (HHcy) causes increased oxidative stress and is an independent risk factor for cardiovascular disease. Oxidative stress is now believed to be a major contributory factor in the development ...
The promoter of cell growth- and RNA protection-associated SND1 gene is activated by endoplasmic reticulum stress in human hepatoma cells
(Biomed Central, 2014-12-11)
Background: Staphyloccocal nuclease domain-containing protein 1 (SND1) is involved in the regulation of gene expression and RNA protection. While numerous studies have established that SND1 protein expression is modulated ...
TWEAK/Fn14 Signaling Is Required for Liver Regeneration after Partial Hepatectomy in Mice
(Public Library of Science, 2014-01)
Background & Aims: Pro-inflammatory cytokines are important for liver regeneration after partial hepatectomy (PH). Expression of Fibroblast growth factor-inducible 14 (Fn14), the receptor for TNF-like weak inducer of ...
Birth size and gestational age in opposite-sex twins as compared to same-sex twins: An individualbased pooled analysis of 21 cohorts
(Nature Publishing, 2018-04-19)
It is well established that boys are born heavier and longer than girls, but it remains unclear whether birth size in twins is affected by the sex of their co-twin. We conducted an individual-based pooled analysis of 21 ...
Genetic and environmental influences on human height from infancy through adulthood at different levels of parental education
(Nature, 2020-05-14)
Genetic factors explain a major proportion of human height variation, but differences in mean stature have also been found between socio-economic categories suggesting a possible effect of environment. By utilizing a ...
Genetic and environmental variation in educational attainment: an individual-based analysis of 28 twin cohorts
(Nature, 2020-07-29)
We investigated the heritability of educational attainment and how it differed between birth cohorts and cultural-geographic regions. A classical twin design was applied to pooled data from 28 cohorts representing 16 ...
Lifestyle Patterns and Weight Status in Spanish Adults: The ANIBES Study
(MDPI, 2017-06)
Limited knowledge is available on lifestyle patterns in Spanish adults. We investigated dietary patterns and possible meaningful clustering of physical activity, sedentary behavior, sleep time, and smoking in Spanish adults ...
Associations Between Birth Size and Later Height From Infancy Through Adulthood: an Individual Based Pooled Analysis of 28 Twin Cohorts Participating in the Codatwins Project
(Elsevier Ireland, 2018-05)
Background: There is evidence that birth size is positively associated with height in later life, but it remains unclear whether this is explained by genetic factors or the intrauterine environment.
Aim: To analyze the ...