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FORTIS: a Live-Cell Assay to Monitor AMPA Receptors Using pH-Sensitive Fluorescence Tags
(Nature, 2021-05-27)
The real-time live fluorescent monitoring of surface AMPA receptors (AMPARs) could open new opportunities for drug
discovery and phenotypic screening concerning neuropsychiatric disorders. We have developed FORTIS, a tool ...
Fluorine Labeling of Nanoparticles and In Vivo 19F Magnetic Resonance Imaging
(American Chemical Society, 2021-03-24)
Fluorinated nanoparticles have increasing applications, but they are still challenging to prepare, especially in the case of water-soluble fluorinated nanoparticles. Herein, a fluorine labeling strategy is presented that ...
Physiology of Basketball - Field Tests. Review Article
(Sciendo, 2021-01)
The game of basketball is characterized by short and intense bouts of activity at medium to high frequency. Basketball entails specific types of movements, physiological requirements and energy sources. The duration of ...
The Oyambre Coastal Terrace: a Detailed Sedimentary Record of the Last Interglacial Stage in Northern Iberia (Cantabrian Coast, Spain)
(Wiley, 2021-05-14)
A detailed study is presented of a 15.3-m-thick Pleistocene coastal terrace located on the Cantabrian coast (northern Spain). Stratigraphic, sedimentological, topographic and micropalaeontological information is combined ...
High-intensity activity according to playing position with different team formations in soccer
(Palacký University Olomouc, 2021-03-29)
[EN] Background: A tactical factor such as playing formation seems to be another influencing factor in the physical performance of elite
soccer players during the match. Some researchers have suggested that distances ...
Valuation of real-estate losses via Monte Carlo simulation
(Routledge Journals, Taylor & Francis, 2020)
The valuation of the exposure to real estate market risk has traditionally been difficult due to the lack of appropriate data, returns that do not follow a normal distribution and a lack of adequate methodology. However, ...
Experimental Devices to Investigate the Long-Term Stability of Phase Change Materials under Application Conditions
(MDPI, 2020-11-10)
An important prerequisite to select a reliable phase change material (PCM) for thermal energy storage applications is to test it under application conditions. In the case of solid–liquid PCM, a large amount of thermal ...
Activity of Pterostilbene Metabolites against Liver Steatosis in Cultured Hepatocytes
(MDPI, 2020-11-20)
Pterostilbene is a dimethyl ether derivative of resveratrol, less metabolized than its analogue, due to the substitution of two hydroxyl groups with methoxyl groups. Nevertheless, the amounts of pterostilbene phase II ...
Site-Selective Aqueous C–H Acylation of Tyrosine-Containing Oligopeptides with Aldehydes
(RSC, 2020-10-06)
The development of useful synthetic tools to label amino acids within a peptide framework for the ultimate modification of proteins in a late-stage fashion is a challenging task of utmost importance within chemical biology. ...
Site-Selective Trifluoromethylation Reactions of Oligopeptides
(Wiley, 2020-06-08)
Site-selective chemical modifications that target proteinogenic amino acid residues complement the methods entailing genetic manipulation, thereby allowing straightforward and rapid access to engineered proteins. The ...