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RIPK3 acts as a lipid metabolism regulator contributing to inflammation and carcinogenesis in non-alcoholic fatty liver disease
(BMJ, 2021-12)
[EN]Objective Receptor-interacting protein kinase 3 (RIPK3) is a key player in necroptosis execution and an emerging metabolic regulator, whose contribution to non-alcoholic fatty liver disease (NAFLD) is controversial. ...
The Tyrosine Phosphatase hPTPRβ Controls the Early Signals and Dopaminergic Cells Viability via the P2X7 Receptor
(MDPI, 2021-11-29)
ATP, one of the signaling molecules most commonly secreted in the nervous system and capable of stimulating multiple pathways, binds to the ionotropic purinergic receptors, in particular, the P2X7 receptor (P2X7R) and ...
On Nonlinear Model Predictive Control for Energy-Efficient Torque-Vectoring
(IEEE-Institute of Electrical and Electronics Engineers, 2021-01)
A recently growing literature discusses the topics of direct yaw moment control based on model predictive control (MPC), and energy-efficient torque-vectoring (TV) for electric vehicles with multiple powertrains. To reduce ...
Antitumor Necrosis Factor Agents to Treat EndoscopicPostoperative Recurrence of Crohn’s Disease: A Nationwide Study With Propensity-Matched Score Analysis
(Lippincott Williams & Wilkins, 2020-08)
INTRODUCTION:Patients with Crohn's disease experiencing endoscopic postoperative recurrence (POR) may benefit from antitumor necrosis factor (TNF) agents but scarce data on this are available. Our aim was to assess the ...
Predictive Value of Carcinoembryonic Antigen in Symptomatic Patients without Colorectal Cancer: A Post-Hoc Analysis within the COLONPREDICT Cohort
(MDPI, 2020-12-02)
We aimed to assess the risk of cancer in patients with abdominal symptoms after a complete colonoscopy without colorectal cancer (CRC), according to the carcinoembryonic antigen (CEA) concentration, as well as its diagnostic ...
Assessment and Selection of Technologies for the Sustainable Development of an R&D Center
(MDPI, 2020-12-03)
The central role of R&D centers in the advancement of technology within industrial enterprises is undeniable and clearly affects their strategies, their competitiveness and their business sustainability. R&D centers assume ...
Incorporation of Antibiotics into Solid Lipid Nanoparticles: A Promising Approach to Reduce Antibiotic Resistance Emergence
(MDPI, 2021-05-10)
Antimicrobial resistance is one of the biggest threats to global health as current antibiotics are becoming useless against resistant infectious pathogens. Consequently, new antimicrobial strategies are urgently required. ...
Adult and Developing Zebrafish as Suitable Models for Cardiac Electrophysiology and Pathology in Research and Industry
(Frontiers Media, 2021-01-13)
The electrophysiological behavior of the zebrafish heart is very similar to that of the human heart. In fact, most of the genes that codify the channels and regulatory proteins required for human cardiac function have their ...
Mechanical Behavior Modeling of Containers and Octabins Made of Corrugated Cardboard Subjected to Vertical Stacking Loads
(MDPI, 2021-05-04)
The aim of this paper is to characterize the mechanical behavior of corrugated cardboard boxes using simple models that allow an approach to the load capacity and the deformation of the boxes. This is very interesting ...
Insights into the Nature of the Active Sites of Pt-WOx/Al2O3 Catalysts for Glycerol Hydrogenolysis into 1,3-Propanediol
(MDPI, 2021-09-27)
The chemo-selective hydrogenolysis of secondary hydroxyls is an important reaction for the production of biomass-derived α,ω-diols. This is the case for 1,3-propanediol production from glycerol. Supported Pt-WOx materials ...