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Colorectal Cancer Genetic Variants Are Also Associated with Serrated Polyposis Syndrome Susceptibility
(BMJ Publishing Group, 2020-10)
Background Serrated polyposis syndrome (SPS) is a clinical entity characterised by large and/ormultiple serrated polyps throughout the colon and increased risk for colorectal cancer (CRC). The basis for SPS genetic ...
Exome Sequencing of Early-Onset Patients Supports Genetic Heterogeneity in Colorectal Cancer
(Springer, 2021-05-27)
Colorectal cancer (CRC) is a complex disease that can be caused by a spectrum of genetic variants ranging from low to high penetrance changes, that interact with the environment to determine which individuals will develop ...
Cholangiocarcinoma 2020: the next horizon in mechanisms and management
(Springer Nature, 2020-06-30)
[EN] Cholangiocarcinoma (CCA) includes a cluster of highly heterogeneous biliary malignant
tumours that can arise at any point of the biliary tree. Their incidence is increasing globally,
currently accounting for ~15% ...
The altered serum lipidome and its diagnostic potential for Non-Alcoholic Fatty Liver (NAFL)-associated hepatocellular carcinoma
(Elsevier, 2021-11)
[EN]Background: Non-alcoholic fatty liver disease (NAFLD) is affecting more people globally. Indeed, NAFLD is a spectrum of metabolic dysfunctions that can progress to hepatocellular carcinoma (NAFLD-HCC). This development ...
Electoral incentives and distributive politics in young democracies: Evidence from Chile
(Elsevier, 2021-10)
[EN]How do electoral incentives and institutional constraints vary as democracies consolidate? Are incumbents more inclined to behave opportunistically during transitions, or when the rules of the game are well established? ...
A reproducible method for biochemical, histological and functional assessment of the effects of ischaemia–reperfusion syndrome in the lower limbsIñig
(Nature Research, 2021-09-29)
[EN]Current methodology described to mimic lower limb ischaemia-reperfusion injury (LL-IRI) does not accurately define the procedures and pressures exerted to induce and maintain ischaemia. In this piece of work, we propose ...
Contrastive focus reduplication and the modification puzzle
(Ubiquity Press, 2020-05-14)
In this short paper we present a so far unnoticed syntactic constraint on contrastive focus-reduplication (CR), a phenomenon that restricts the semantics of the reduplicated element to a prototypical meaning (but has other ...
Towards a more precise therapy in cancer: Exploring epigenetic complexity
(Elsevier, 2020-08)
A plethora of preclinical evidences suggests that pharmacological targeting of epigenetic dysregulation is a potent strategy to combat human diseases. Nevertheless, the implementation of epidrugs in clinical practice is ...
Influence of Pitch Size on Short-Term High Intensity Actions and Body Impacts in Soccer Sided Games
(Sciendo, 2021-03-31)
The aim of this study was to compare external training loads between small-sided games (SSGs) and largesided games (LSGs) in soccer players. Twenty outfield soccer players (14.8 ± 0.6 years old) who competed in the Spanish ...
Open BOK on Software Engineering Educational Context: A Systematic Literature Review
(MDPI, 2020-08-24)
In this review, a Systematic Literature Review (SLR) on Open Body of Knowledge (BOK) is presented. Moreover, the theoretical base to build a model for knowledge description was created, and it was found that there is a ...