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Now showing items 1291-1300 of 2620
What are the Topics You Care about Making Trials in Lupus More Effective? Results of an Open Space Meeting of International Lupus Experts
(BMJ Publishing Group, 2021-05-20)
Despite promising candidates for new therapeutic options in the treatment of systemic lupus erythematosus (SLE), many clinical trials have failed in the past few years. The disappointing results have been at least partly ...
Unraveling the Effect of Singlet Oxygen on Metal-O2 Batteries: Strategies Toward Deactivation
(Frontiers Media, 2020-07-22)
Aprotic metal-O(2)batteries have attracted the interest of the research community due to their high theoretical energy density that target them as potential energy storage systems for automotive applications. At present, ...
Integrating Mathematics and Science Teaching in the Context of Education for Sustainable Development: Design and Pilot Implementation of a Teaching-Learning Sequence about Air Quality with Pre-Service Primary Teachers
(MDPI, 2021-04-18)
This article presents an interdisciplinary teaching–learning sequence (TLS) about air quality for pre-service primary teachers using an organic learning garden. The design involved a curricular integration of concepts and ...
Synthetic Conjugates of Ursodeoxycholic Acid Inhibit Cystogenesis in Experimental Models of Polycystic Liver Disease
(Wiley, 2020-09-22)
Background and Aims Polycystic liver diseases (PLDs) are genetic disorders characterized by progressive development of symptomatic biliary cysts. Current surgical and pharmacological approaches are ineffective, and liver ...
Analysis of Fine Motor Skills in Essential Tremor: Combining Neuroimaging and Handwriting Biomarkers for Early Management
(Frontiers Media, 2021-06-08)
[EN] Essential tremor (ET) is a highly prevalent neurological disorder characterized by actioninduced
tremors involving the hand, voice, head, and/or face. Importantly, hand tremor
is present in nearly all forms of ET, ...
In Vitro P38MAPK Inhibition in Aged Astrocytes Decreases Reactive Astrocytes, Inflammation and Increases Nutritive Capacity After Oxygen-Glucose Deprivation
(Impact Journals LLC, 2021-03-15)
Proper astroglial functioning is essential for the development and survival of neurons and oligodendroglia under physiologic and pathological circumstances. Indeed, malfunctioning of astrocytes represents an important ...
Lean Manufacturing and Environmental Sustainability: The Effects of Employee Involvement, Stakeholder Pressure and ISO 14001
(MDPI, 2020-09-04)
This paper explores the relationships between lean manufacturing (LM), the promotion of green practices, employee involvement, pressure to take actions against environmental issues, the adoption of an ISO 14001-based ...
Sephin1 Protects Neurons against Excitotoxicity Independently of the Integrated Stress Response
(MDPI, 2020-08-24)
Sephin1 is a derivative of guanabenz that inhibits the dephosphorylation of the eukaryotic initiation factor 2 alpha (eIF2α) and therefore may enhance the integrated stress response (ISR), an adaptive mechanism against ...
Landsat and Sentinel-2 Based Burned Area Mapping Tools in Google Earth Engine
(MDPI, 2021-02-23)
Four burned area tools were implemented in Google Earth Engine (GEE), to obtain regular processes related to burned area (BA) mapping, using medium spatial resolution sensors (Landsat and Sentinel-2). The four tools are ...
Patterns of Change in Dietary Habits and Physical Activity during Lockdown in Spain Due to the COVID-19 Pandemic
(MDPI, 2021-01-21)
Background: Lockdown due to COVID-19 influenced food habits and lifestyles with potential negative health impact. This study aims to identify patterns of change in eating habits and physical activity during COVID-19 lockdown ...