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Now showing items 1441-1450 of 2620
A UHPLC-Mass Spectrometry View of Human Melanocytic Cells Uncovers Potential Lipid Biomarkers of Melanoma
(MDPI, 2021-10-08)
Melanoma is the deadliest form of skin cancer due to its ability to colonize distant sites and initiate metastasis. Although these processes largely depend on the lipid-based cell membrane scaffold, our understanding of ...
Delta(9)-Tetrahydrocannabinol Promotes Oligodendrocyte Development and CNS Myelination in Vivo
(Wiley, 2021-03)
Delta(9)-Tetrahydrocannabinol (THC), the main bioactive compound found in the plantCannabis sativa, exerts its effects by activating cannabinoid receptors present in many neural cells. Cannabinoid receptors are also ...
Astrocytic Atrophy as a Pathological Feature of Parkinson's Disease with LRRK2 Mutation
(Springer, 2021-03-30)
The principal hallmark of Parkinson's disease (PD) is the selective neurodegeneration of dopaminergic neurones. Mounting evidence suggests that astrocytes may contribute to dopaminergic neurodegeneration through decreased ...
Comparing Bayesian Spatial Conditional Overdispersion and the Besag–York–Mollié Models: Application to Infant Mortality Rates
(MDPI, 2021-01-31)
In this paper, we review overdispersed Bayesian generalized spatial conditional count data models. Their usefulness is illustrated with their application to infant mortality rates from Colombian regions and by comparing ...
Fluorescence Microscopy of the HIV-1 Envelope
(MDPI, 2020-03-21)
Human immunodeficiency virus (HIV) infection constitutes a major health and social issue worldwide. HIV infects cells by fusing its envelope with the target cell plasma membrane. This process is mediated by the viral Env ...
Associative Conditioning Is a Robust Systemic Behavior in Unicellular Organisms: An Interspecies Comparison
(Frontiers Media, 2021-07-19)
The capacity to learn new efficient systemic behavior is a fundamental issue of contemporary biology. We have recently observed, in a preliminary analysis, the emergence of conditioned behavior in some individual amoebae ...
Genotyping Study of Salmonella 4,[5],12:i:- Monophasic Variant of Serovar Typhimurium and Characterization of the Second-Phase Flagellar Deletion by Whole Genome Sequencing
(MDPI, 2020-12-21)
After Salmonella Enteritidis and S. Typhimurium, S. 4,[5],12:i:- is the most reported serovar in human clinical cases. During the past 20 years, many tools have been used for its typing and second-phase flagellar deletion ...
A common fungicide impairs stream ecosystem functioning through effects on aquatic hyphomycetes and detritivorous caddisflies
(Academic Press-Elsevier, 2020-06-01)
Fungicides can reach streams through runoff or adhered to leaf litter, and have the potential to adversely affect processes such as litter decomposition and associated communities. This study investigated the effects of ...
A Quasi-Experimental Intervention Protocol to Characterize the Factors that Influence the Acceptance of New Foods by Infants: Mothers' Diet and Weaning Method. Dastatuz Project
(BioMed Central, 2021-05-13)
Background: Children usually refuse to eat and taste fruits and vegetables; and turning unhealthy eating habits around is an important social challenge in industrialized countries. The Dastatuz project aims to study children ...
Vibron-assisted spin excitation in a magnetically anisotropic molecule
(Nature, 2020-04)
The electrical control and readout of molecular spin states are key for high-density storage. Expectations are that electrically-driven spin and vibrational excitations in a molecule should give rise to new conductance ...