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Super-Resolution STED Microscopy in live Brain Tissue
(Elsevier, 2021-08)
STED microscopy is one of several fluorescence microscopy techniques that permit imaging at higher spatial resolution than what the diffraction-limit of light dictates. STED imaging is unique among these super-resolution ...
The shape of higher-dimensional state space: Bloch-ball analog for a qutrit
(Verein zur Förderung des Open Access Publizierens in den Quantenwissenschaften, 2021-06-29)
[EN] Geometric intuition is a crucial tool to
obtain deeper insight into many concepts
of physics. A paradigmatic example of its
power is the Bloch ball, the geometrical
representation for the state space of the
simplest ...
Sea Bass Primary Cultures versus RTgill-W1 Cell Line: Influence of Cell Model on the Sensitivity to Nanoparticles
(MDPI, 2021-11-20)
Determination of acute toxicity to vertebrates in aquatic environments is mainly performed following OECD test guideline 203, requiring the use of a large number of fish and with mortality as endpoint. This test is also ...
Integrating Social Innovation into the Curriculum of Higher Education Institutions in Latin America: Insights from the Students4Change Project
(MDPI, 2021-05-11)
In the last two decades, social innovation (SI) and social entrepreneurship (SE) have gained relevance and interest within the framework of academia at international level. Higher education institutions (HEIs) are key ...
Design and Validation of a Process Based on Cationic Niosomes for Gene Delivery into Novel Urine-Derived Mesenchymal Stem Cells
(MDPI, 2021-05-11)
Background: Mesenchymal stem cells (MSCs) are stem cells present in adult tissues. They can be cultured, have great growth capacity, and can differentiate into several cell types. The isolation of urine-derived mesenchymal ...
An Epilepsy-Causing Mutation Leads to Co-Translational Misfolding of the Kv7.2 Channel
(Springer, 2021-05-21)
BACKGROUND: The amino acid sequence of proteins generally carries all the necessary information for acquisition of native conformations, but the vectorial nature of translation can additionally determine the folding outcome. ...
Sustained CHK2 activity, but not ATM activity, is critical to maintain a G1 arrest after DNA damage in untransformed cells
(BMC, 2021-02-19)
BACKGROUND: The G1 checkpoint is a critical regulator of genomic stability in untransformed cells, preventing cell cycle progression after DNA damage. DNA double-strand breaks (DSBs) recruit and activate ATM, a kinase which ...
Novel CircRNA Discovery in Sheep Shows Evidence of High Backsplice Junction Conservation
(Springer Nature, 2021-01-11)
Circular RNAs (circRNAs) are covalently closed circular non-coding RNAs. Due to their structure, circRNAs are more stable and have longer half-lives than linear RNAs making them good candidates for disease biomarkers. ...
CO2 cryogenic milling of Inconel 718: cutting forces and tool wear Author links open overlay panel
(Elsevier, 2020-07)
Machining Inconel 718 alloy is a challenge due to its low machinability. This thermal resis-tant alloy combines high strength even at high temperatures with strain hardening tendency that causes high forces and extreme ...
Nature more than nurture affects the growth rate of mussels
(Springer Nature, 2020-02-26)
We tested the hypothesis that environmental trophic conditions prominent during the growing period (nurture conditions) can modify the differing physiological profiles between fast (F)- and slow (S)-growing juveniles of ...