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Solid-phase synthesis of imprinted nanoparticles as artificial antibodies against the C-terminus of the cannabinoid CB1 receptor: exploring a viable alternative for bioanalysis
(Springer, 2021-11)
[EN]The production of artificial anti-CB1 antibodies in nanoparticle format is described using the solid-phase imprinting approach. Instead of whole protein imprinting, a linear C-terminus sequence of the receptor comprising ...
A Behavioural Model of Minority Language Shift: Theory and Empirical Evidence
(Public Library Of Science, 2021-06-04)
Natural languages with their speech communities tend to compete for speakers, very much like firms compete for market shares. As a result, some languages suffer a shifting pressure which might lead them to their extinction. ...
Non-Linear Optical Properties of Er3+–Yb3+-Doped NaGdF4 Nanostructured Glass–Ceramics
(MDPI, 2020-07-21)
Transparent oxyfluoride glass–ceramics containing NaGdF4 nanocrystals were prepared by melt-quenching and doped with Er3+ (0.5 mol%) and different amounts of Yb3+ (0–2 mol%). The selected dopant concentration the crystallization ...
Electrical features of the diabetic myocardium. Arrhythmic and cardiovascular Safety considerations in diabetes
(Frontiers Media, 2021-07-08)
[EN] Diabetes is a chronic metabolic disease characterized by hyperglycemia in the absence
of treatment. Among the diabetes-associated complications, cardiovascular disease is
the major cause of mortality and morbidity ...
A New Sol-Gel Route Towards Nd3+-doped SiO2-LaF3 Glass-Ceramics for Photonic Applications
(Royal Society Of Chemistry, 2020-12-01)
Glass-ceramic materials with composition 0.9Nd(3+)-80SiO(2)-20LaF(3) were successfully obtained and further heat-treated at 450 degrees C for 6 h. Stable and homogeneous LaF3 nanoparticle suspensions with and without Nd3+ ...
Energy Test of an Efficient Random Laser Emission Collecting System
(SPIE-Society of Photo-Optical Instrumentation Engineers, 2021-01-29)
The problem of light collection in random lasers (RLs) is addressed. As the radiation emitted by this system is Lambertian due to its spatial incoherence, a device based on an ellipsoidal revolution mirror is designed, ...
Sustainability Assessment of Pasture-Based Dairy Sheep Systems: A Multidisciplinary and Multiscale Approach
(MDPI, 2021-04-02)
This article describes a novel methodological approach for the integrated sustainability assessment of pasture-based dairy sheep systems. Most studies on livestock system sustainability focus on animal production, farm ...
Anti-miR-518d-5p Overcomes Liver Tumor Cell Death Resistance Through Mitochondrial Activity
(Springer Nature, 2021-05-28)
Dysregulation of miRNAs is a hallmark of cancer, modulating oncogenes, tumor suppressors, and drug responsiveness. The multi-kinase inhibitor sorafenib is one of the first-line drugs for advanced hepatocellular carcinoma ...
Transferrin Isoforms, Old but New Biomarkers in Hereditary Fructose Intolerance
(MDPI, 2021-06-30)
Hereditary Fructose Intolerance (HFI) is an autosomal recessive inborn error of metabolism characterised by the deficiency of the hepatic enzyme aldolase B. Its treatment consists in adopting a fructose-, sucrose-, and ...
Molecular and Electrophysiological Role of Diabetes-Associated Circulating Inflammatory Factors in Cardiac Arrhythmia Remodeling in a Metabolic-Induced Model of Type 2 Diabetic Rat
(MDPI, 2021-06-25)
Background: Diabetic patients have prolonged cardiac repolarization and higher risk of arrhythmia. Besides, diabetes activates the innate immune system, resulting in higher levels of plasmatic cytokines, which are described ...