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Now showing items 2211-2220 of 2620
An Approach to the Synthesis of a Hepatitis C Virus Inhibitor through a Proline-Catalyzed 1,3-Dipolar Cycloaddition Using Acrolein
(Thieme, 2021-09-06)
An efficient and easy protocol for performing 1,3-dipolar cycloaddition using azomethine ylides and acrolein is presented. The reaction catalyzed by d-proline allows the synthesis of C-3 unsubstituted pyrrolidines. The ...
Enantioselective Synthesis of Tropanes: Brønsted Acid Catalyzed Pseudotransannular Desymmetrization
(Wiley-VCH, 2020-02-10)
The enantioselective synthesis of tropanols has been accomplished through chiral phosphoric acid catalyzed pseudotransannular ring opening of 1-aminocyclohept-4-ene-derived epoxides. The reaction proceeds together with the ...
Catalytic enantioselective domino Michael/transannular aldol reaction under bifunctional catalysis
(Royal Society of Chemistry, 2020-09-28)
The enantioselective Michael reaction catalyzed by a bifunctional tertiary amine/squaramide has been used to trigger a Michael/transannular aldol cascade process that leads to densely substituted bicyclo[5.4.0]undecanes ...
γ-Substituted Allenic Amides in the Phosphine-Catalyzed Enantioselective Higher Order Cycloaddition with Azaheptafulvenes
(American Chemical Society, 2020-05-28)
Racemic γ-substituted allenes undergo enantioselective higher order [8 + 2]-cycloaddition with azaheptafulvenes using a chiral amino acid derived amidophosphine as catalyst, providing the corresponding azaazulenoid ...
Cp*Co(III)-Catalyzed C−H Hydroarylation of Alkynes and Alkenes and Beyond: A Versatile Synthetic Tool
(ACS, 2020-09-15)
The use of earth-abundant first-row transition
metals, such as cobalt, in C−H activation reactions for the
construction and functionalization of a wide variety of structures
has become a central topic in synthetic ...
Palladium-mediated synthesis and biological evaluation of C-10b substituted Dihydropyrrolo[1,2-b]isoquinolines as antileishmanial agents
(Elsevier, 2021-04-16)
The development of new molecules for the treatment of leishmaniasis is, a neglected parasitic disease, is
urgent as current anti-leishmanial therapeutics are hampered by drug toxicity and resistance. The pyrrolo[
1,2-b ...
Dragon Ball on the Basque public TV: influence on viewers’ language attitudes and practices
(Taylor & Francis, 2021-07-01)
Dragon Ball was highly popular among different generations in the Basque Country. The anime TV series was broadcast in Galician, Catalan and Basque practically at the same time in 1990. The translation and dubbing into ...
Basque informal talk increasingly restricted to men: The role of gender in the form of address hika
(DEWS Publication, 2021-03)
Many languages make a T/V distinction when addressing an interlocutor, and Basque also has two main levels of
formality: zuka (formal) and hika (informal). The peculiarity of the Basque informal form of address hika is ...
Dynamic Nucleophilic Aromatic Substitution of Tetrazines
(Wiley, 2021-08-23)
A dynamic nucleophilic aromatic substitution of tetrazines (SNTz) is presented herein. It combines all the advantages of dynamic covalent chemistry with the versatility of the tetrazine moiety. Indeed, libraries of compounds ...
Cost of Production Loss for Long-term Disability due to Road Crashes
(University of Zagreb, Faculty of Transport and Traffic Sciences, 2020)
[EU] Traffic accidents leave lifelong after-effects and if the victim is disabled, they produce a production loss due to the differential in income that will be lost. This average value is very divergent in European ...