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Molecular diagnosis of distal renal tubular acidosis in Tunisian patients: proposed algorithm for Northern Africa populations for the ATP6V1B1, ATP6V0A4 and SCL4A1 genes
(Biomed Central, 2013-11)
Background: Primary distal renal tubular acidosis (dRTA) caused by mutations in the genes that codify for the H+ -ATPase pump subunits is a heterogeneous disease with a poor phenotype-genotype correlation. Up to now, large ...
Synthetic scope and DFT analysis of the chiral binap-gold(I) complex-catalyzed 1,3-dipolar cycloaddition of azlactones with alkenes
(Beilstein Institut, 2013-11)
he 1,3-dipolar cycloaddition between glycine-derived azlactones with maleimides is efficiently catalyzed by the dimeric chiral complex [(S-a)-Binap.AuTFA](2). The alanine-derived oxazolone only reacts with tert-butyl ...
A colorectal cancer genome-wide association study in a Spanish cohort identifies two variants associated with colorectal cancer risk at 1p33 and 8p12
(BioMed Central, 2013-01)
Background: Colorectal cancer (CRC) is a disease of complex aetiology, with much of the expected inherited risk being due to several common low risk variants. Genome-Wide Association Studies (GWAS) have identified 20 CRC ...
Evaluation of Alpha 1-Antitrypsin and the Levels of mRNA Expression of Matrix Metalloproteinase 7, Urokinase Type Plasminogen Activator Receptor and COX-2 for the Diagnosis of Colorectal Cancer
(Public Library of Science, 2013-01-02)
Background: Colorectal cancer (CRC) is the second most common cause of death from cancer in both men and women in the majority of developed countries. Molecular tests of blood could potentially provide this ideal screening ...
Effective and Robust Generalized Predictive Speed Control of Induction Motor
(Hindawi Publishing Corporation, 2013-10-16)
This paper presents and validates a new proposal for effective speed vector control of induction motors based on linear Generalized Predictive Control (GPC) law. The presented GPC-PI cascade configuration simplifies the ...
In the footstep of Hermes: the meaning of the hermeneutics and symbolism
(A. Murray, J. Roffe, M. Sharpe, 2013)
[EN] The meaning of hermeneutics is not something exclusive to hermeneutics; it is not something the hermeneutical enterprise dominates, masters, or even manages. Rather, hermeneutics must understand itself as an activity ...
Multi-drug resistance profiles and the genetic features of Acinetobacter baumannii isolates from Bolivia
(Journal of Infection in Developing Countries, 2013-04)
Introduction: Acinetobacter baumannii is opportunistic in debilitated hospitalised patients. Because information from some South American countries was previously lacking, this study examined the emergence of multi-resistant ...
Increased physical activity is not enough to recover astrocytic population from dark-rearing. Synergy with multisensory enrichment is required
(Frontiers Research Foundation, 2013-10-04)
Elimination of sensory inputs (deprivation) modifies the properties of the sensory cortex and serves as a model for studying plasticity during postnatal development. Many studies on the effects of deprivation have been ...
Design of an optimised wheel profile for rail vehicles operating on two track gauges
(Taylor & Francis, 2013-01)
This paper sets out an optimum synthesis methodology for wheel profiles of railway vehicles in order to secure good dynamic behaviour with different track configurations. Specifically, the optimisation process has been ...
Malaria Vaccine Adjuvants: Latest Update and Challenges in Preclinical and Clinical Research
(Hindawi Publishing Corporation, 2013)
There is no malaria vaccine currently available, and the most advanced candidate has recently reported a modest 30% efficacy against clinical malaria. Although many efforts have been dedicated to achieve this goal, the ...