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Large Volume Self-powered Disposable Microfluidics by the Integration of Modular Polymer Micropumps with Plastic Microfluidic Cartridges
(ACS, 2020-12-10)
Microfluidic microsystems are often designed to analyse samples of small volume of fluid, however, some applications require the analysis of larger volumes. The ideal miniaturized microfluidic analytical device should be ...
Ionogel-based hybrid polymer-paper handheld platform for nitrite and nitrate determination in water samples.
(Elsevier, 2022-05)
[EN] Nowadays, miniaturization and portability are crucial characteristics that need to be considered for the development of water monitoring systems. In particular, the use of handheld technology, including microfluidics, ...
Advances in Microtechnology for Improved Cytotoxicity Assessment
(Frontiers Media, 2020-11-20)
In vitro cytotoxicity testing is essential in the pharmaceutical and environmental industry to study the effects of potential harmful compounds for human health. Classical assays present several disadvantages: they are ...
High-Resolution 3D Printing Fabrication of a Microfluidic Platform for Blood Plasma Separation
(MDPI, 2022)
Additive manufacturing technology is an emerging method for rapid prototyping, which enables the creation of complex geometries by one-step fabrication processes through a layer-by-layer approach. The simplified fabrication ...
Type 1 Diabetes Mellitus reversal via implantation of magnetically purified microencapsulated pseudoislets
(Elsevier, 2019-02-10)
Microencapsulation of pancreatic islets for the treatment of Type I Diabetes Mellitus (T1DM) generates a high quantity of empty microcapsules, resulting in high therapeutic graft volumes that can enhance the host’s immune ...
Extracellular matrix protein microarray-based biosensor with single cell resolution: Integrin profiling and characterization of cell-biomaterial interactions
(Elsevier, 2019-08-06)
In the search of biomaterials that promote cell adhesion, it is crucial to explore the integrin-substrate dynamic interactions given in a certain cell type to design successful biofunctionalization strategies. Here, we use ...
Alginate Bead Biosystem for the Determination of Lactate in Sweat Using Image Analysis
(MDPI, 2021-10-09)
Lactate is present in sweat at high concentrations, being a metabolite of high interest in sport science and medicine. Therefore, the potential to determine lactate concentrations in physiological fluids, at the point of ...
TiO2 Nanotubes Alginate Hydrogel Scaffold for Rapid Sensing of Sweat Biomarkers: Lactate and Glucose
(American Chemical Society, 2021-08-11)
Versatile sensing matrixes are essential for the development of enzyme-immobilized optical biosensors. A novel three-dimensional titanium dioxide nanotubes/alginate hydrogel scaffold is proposed for the detection of sweat ...
Development of an alginate/TiO2-based microfluidic biosystem for chrono-sampling and sensing of glucose in artificial sweat
(Elsevier, 2023-05)
Glucose is an analyte of great importance, both in the clinical and sports fields. As an alternative to standard blood analysis, sweat arises as an easily accessible, non-invasive biofluid, as well as a great candidate to ...
An electroactive and thermo-responsive material for the capture and release of cells
(Elsevier, 2021-06-05)
Non-invasive collection of target cells is crucial for research in biology and medicine. In this work, we combine a thermo-responsive material, poly(N-isopropylacrylamide), with an electroactive material, poly(3,4-ethyle ...