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Beneficial Effects of Opuntia spp. on Liver Health
(MDPI, 2023-05-29)
The genus Opuntia spp. includes plants capable of growing in arid, temperate and tropical climates. The vast majority of wild species grow in Mexico, but O. ficus-indica (prickly pear or nopal) is cultivated around the ...
Computational and Experimental Evaluation of the Immune Response of Neoantigens for Personalized Vaccine Design
(MDPI, 2023-05-19)
In the last few years, the importance of neoantigens in the development of personalized antitumor vaccines has increased remarkably. In order to study whether bioinformatic tools are effective in detecting neoantigens that ...
Stability of Monoclonal Antibodies as Solid Formulation for Auto-Injectors: A Pilot Study
(MDPI, 2023-07-30)
Drug adherence is a significant medical issue, often responsible for sub-optimal outcomes during the treatment of chronic diseases such as rheumatoid or psoriatic arthritis. Monoclonal antibodies (which are exclusively ...
Assessment of Different Niosome Formulations for Optogenetic Applications: Morphological and Electrophysiological Effects
(MDPI, 2023-07-01)
Gene therapy and optogenetics are becoming promising tools for treating several nervous system pathologies. Currently, most of these approaches use viral vectors to transport the genetic material inside the cells, but ...
Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses
(Elsevier, 2023-04)
Subunit vaccines typically require co-administration with an adjuvant to elicit protective immunity, adding development hurdles that can impede rapid pandemic responses. To circumvent the need for adjuvant in a severe acute ...
Influence of methyl donor nutrients as epigenetic regulators in colorectal cancer: A systematic review of observational studies
(Baishideng, 2023)
BACKGROUNDDietary methyl donors might influence DNA methylation during carcinogenesis of colorectal cancer (CRC). However, whether the influence of methyl donor intake is modified by polymorphisms in such epigenetic ...
Zeolites as Ingredients of Medicinal Products
(MDPI, 2023-04-28)
Development of new medicinal products for particular therapeutic treatment or for better manipulations with better quality and less side effects are possible as a result of advanced inorganic and organic materials application, ...
High resolution and fidelity 3D printing of Laponite and alginate ink hydrogels for tunable biomedical applications
(Elsevier, 2023-06)
The formulation of hydrogels that meet the necessary flow characteristics for their extrusion-based 3D printing while providing good printability, resolution, accuracy and stability, requires long development processes. ...
Tumour-derived extracellular vesicle based vaccines for melanoma treatment
(Springer, 2023-05)
The interest of extracellular vesicles (EVs) in cancer immunotherapy is increasing every day. EVs are lipid bilayer vesicles released by most cells, which contain the molecular signature of their parent cell. Melanoma-derived ...
Vegetable By-Products as Alternative and Sustainable Raw Materials for Ruminant Feeding: Nutritive Evaluation and Their Inclusion in a Novel Ration for Calf Fattening
(MDPI, 2023-04-18)
This research aimed to evaluate the nutritional composition, in vitro digestibility, and gas production kinetics of 15 vegetable by-products generated by the agri-food industry compared with corn silage as a reference raw ...