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A Tunable Generator of Instances of Permutation-Based Combinatorial Optimization Problems
(2016-04)
[EN]In this paper, we propose a tunable generator of instances of permutation-based Combinatorial Optimization Problems. Our approach is based on a probabilistic model for permutations, called the Generalized Mallows model. ...
An Evaluation of Methods for Estimating the Number of Local Optima in Combinatorial Optimization Problems
(MIT Press, 2013-11-01)
[EN] The solution of many combinatorial optimization problems is carried out by metaheuristics, which generally make use of local search algorithms. These algorithms use some kind of neighborhood structure over the search ...
On a Common Mistake in the Description of the Photoelectric Effect
(AIP, 2019-11-01)
The photoelectric effect is one of the key experiments taught during first- or second-year university and high school modern physics courses. It is usually the first experiment to introduce light quantization and the concept ...
Wearable Slot Antenna at 2.45 GHz for Off-Body Radiation: Analysis of Efficiency,Frequency Shift, and Body Absorption
(Wiley, 2017-09-12)
The interaction of body-worn antennas with the human body causes a significant decrease in antenna efficiency and a shift in resonant frequency. A resonant slot in a small conductive box placed on the body has been shown ...
Detailed dissection of UBE3A-mediated DDI1 ubiquitination.
(Frontiers, 2019-05-03)
The ubiquitin E3 ligase UBE3A has been widely reported to interact with the proteasome, but it is still unclear how this enzyme regulates by ubiquitination the different proteasomal subunits. The proteasome receptor DDI1 ...
alpha-Branched Ketone Dienolates: Base-Catalyzed Generation and Regio- and Enantioselective Addition Reactions
(Wiley-VCH, 2019-05-14)
In this study, the unique capacity of bifunctional Brønsted bases to generate α-branched ketone dienolates and control both site- and stereoselectivity of their addition reactions to representative classes of carbon ...
The CODATwins Project: The Cohort Description of Collaborative Project of Development of Anthropometrical Measures in Twins to Study Macro-Environmental Variation in Genetic and Environmental Effects on Anthropometric Traits
(2015-05-27)
For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular,
height and body mass index (BMI, calculated as kg/m2) have been under intensive genetic research.
However, ...
Genetic and environmental effects on body mass index from infancy to the onset of adulthood: an individual-based pooled analysis of 45 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) study
(Elsevier, 2016-07-13)
Background: Both genetic and environmental factors are known to affect body mass index (BMI), but detailed understanding of how their effects differ during childhood and adolescence is lacking. Objectives: We analyzed the ...
Enantioselective Construction of Tetrasubstituted Stereogenic Carbons through Brønsted Base Catalyzed Michael Reactions: α´-Hydroxy Enones as Key Enoate Equivalent
(ACS, 2014-11-25)
Catalytic and asymmetric Michael reactions constitute very powerful tools for the construction of new C–C bonds in synthesis, but most of the reports claiming high selectivity are limited to some specific combinations of ...