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In Vitro and In Vivo Evaluation of a Folate-Targeted Copolymeric Submicrohydrogel Based on N-Isopropylacrylamide as 5-Fluorouracil Delivery System
(MDPI, 2011-09)
Folate-targeted poly[(p-nitrophenyl acrylate)-co-(N-isopropylacrylamide)] nanohydrogel (F-SubMG) was loaded with 5-fluorouracil (5-FU) to obtain low (16.3 +/- 1.9 mu g 5-FU/mg F-SubMG) and high (46.8 +/- 3.8 mu g 5-FU/mg ...
Use of generalised additive models to categorise continuous variables in clinical prediction
(BioMed Central, 2013-06-26)
Background: In medical practice many, essentially continuous, clinical parameters tend to be categorised by physicians for ease of decision-making. Indeed, categorisation is a common practice both in medical research and ...
Asymptotic Hyperstability of a Class of Linear Systems under Impulsive Controls Subject to an Integral Popovian Constraint
(Hindawi Publishing Corporation, 2013)
This paper is focused on the study of the important property of the asymptotic hyperstability of a class of continuous-time dynamic systems. The presence of a parallel connection of a strictly stable subsystem to an ...
Best Proximity Points of Generalized Semicyclic Impulsive Self-Mappings: Applications to Impulsive Differential and Difference Equations
(Hindawi Publishing Corporation, 2013)
This paper is devoted to the study of convergence properties of distances between points and the existence and uniqueness of best proximity and fixed points of the so-called semicyclic impulsive self-mappings on the union ...
Resveratrol prevents inflammation-dependent hepatic melanoma metastasis by inhibiting the secretion and effects of interleukin-18
(BioMed Central, 2011-05)
Background: Implantation and growth of metastatic cancer cells at distant organs is promoted by inflammation-dependent mechanisms. A hepatic melanoma metastasis model where a majority of metastases are generated via ...
Clinical factors associated with a Candida albicans Germ Tube Antibody positive test in Intensive Care Unit patients
(BioMed Central, 2011-03)
Background: Poor outcomes of invasive candidiasis (IC) are associated with the difficulty in establishing the microbiological diagnosis at an early stage. New scores and laboratory tests have been developed in order to ...
Pumped double quantum dot with spin-orbit coupling
(Springer, 2011-03)
We study driven by an external electric field quantum orbital and spin dynamics of electron in a one-dimensional double quantum dot with spin-orbit coupling. Two types of external perturbation are considered: a periodic ...
Aspects of quality control of wind profiler measurements in complex topography
(Copernicus Gesellschaft, 2014)
It is well known in the scientific community that some remote sensing instruments assume that sample volumes present homogeneous conditions within a defined meteorological profile. At complex topographic sites and under ...
Biotic vs. Abiotic Control of Decomposition: A Comparison of the Effects of Simulated Extinctions and Changes in Temperature
(Public Library of Science, 2014-01)
The loss of species is known to have significant effects on ecosystem functioning, but only recently has it been recognized that species loss might rival the effects of other forms of environmental change on ecosystem ...
Towards complex system design and management in the engineering domain – the smart grid challenge
(Lawrence Erlbaum Associates, 2013-06-30)
Our world is facing a significant challenge from climate change and global warming, coupled with an increased awareness about the importance of preserving the environment. This challenge calls for us to use our resources ...