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Now showing items 281-290 of 292
Sustained increase of PKA activity in the post-commissural putamen of dyskinetic monkeys
(Springer, 2014-04-05)
Levodopa-induced dyskinesias (LID) are a frequent complication of Parkinson's disease pharmacotherapy that causes significant disability and narrows the therapeutic window. Pharmacological management of LID is challenging ...
AC and DC technology in microgrids: a review
(Elsevier, 2014-12-05)
Microgrids are a suitable, reliable and clean solution to integrate distributed generation into the mains grid. Microgrids can present both AC and DC distribution lines. The type of distribution conditions the performance ...
The effect of hydroxylated fatty acid-containing phospholipids in the remodeling of lipid membranes
(Elsevier B.V., 2014-01-24)
The synthetic fatty acid 2-hydroxyoleic acid (2OHOA) is an antitumor drug that regulates membrane lipid composition and structure. An important effect of this drug is the restoration of sphingomyelin (SM) levels in cancer ...
Stability of CuZnOAl2O3/HZSM-5 and CuFe2O4/HZSM-5 catalysts in dimethyl ether steam reforming operating in reaction-regeneration cycles
(Elsevier, 2014-05-21)
The study focuses on the regenerability of bifunctional catalysts prepared with different metallic functions (CuZnOAl2O3 and CuFe2O4 spinel) and HZSM-5 zeolite (SiO2/Al2O3 = 30) as the acid function. These catalysts have ...
Genetic and metabolic determinants of methotrexate-induced mucositis in pediatric acute lymphoblastic leukemia
(Springer Nature, 2014-11-04)
Methotrexate (MTX) is an effective and toxic chemotherapeutic drug in the treatment of pediatric acute lymphoblastic leukemia(ALL). In this prospective study, we aimed to identify metabolic and genetic determinants of MTX ...
Influence of Animal-Assisted Therapy (AAT) on the Attachment Representations of Youth in Residential Care
(Elsevier, 2014-04-18)
This study evaluates the influence of Animal-Assisted Therapy (AAT) on the attachment representations of a group of adolescents in residential care who suffered traumatic childhood experiences and exhibited mental health ...
Pharmacogenetics of MicroRNAs and MicroRNAs Biogenesis Machinery in Pediatric Acute Lymphoblastic Leukemia
(Public Library Science, 2014-03-10)
Despite the clinical success of acute lymphoblastic leukemia (ALL) therapy, toxicity is frequent. Therefore, it would be useful to identify predictors of adverse effects. In the last years, several studies have investigated ...
An insight into the reactions occurring during the chemical activation of bone char
(Elsevier, 2014-04-24)
The valorisation of animal wastes by pyrolysis has shown to be of interest, due to the versatility of the main compound of char, hydroxyapatite (HAP), which can be used in catalysis, electrochemistry, and adsorption. The ...
Pitch Based Wind Turbine Intelligent Speed Setpoint Adjustment Algorithms
(MDPI, 2014-06)
This work is aimed at optimizing the wind turbine rotor speed setpoint algorithm. Several intelligent adjustment strategies have been investigated in order to improve a reward function that takes into account the power ...
Sex of preceding sibling and anthropometrics of subsequent offspring at birth and in young adulthood: a population-based study in Sweden
(Wiley, 2014-05-13)
In many mammal species with sexual dimorphism producing sons is energetically more demanding to the mother than producing daughters. Although some studies in humans have suggested that offspring born after a brother have ...