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The ABC of Generalized Coordination Numbers and Their Use as a Descriptor in Electrocatalysis
(Wiley, 2023-07)
The quest for enhanced electrocatalysts can be boosted by descriptor-based analyses. Because adsorption energies are the most common descriptors, electrocatalyst design is largely based on brute-force routines that comb ...
Claves para desarrollar contextos de aprendizaje inclusivos para el alumnado con enfermedades raras
(Universidad de Murcia, 2023)
En este artículo, de carácter teórico, y a partir de la revisión de la literatura científica sobre la inclusión educativa del alumnado con Enfermedades Raras (ER) y de las orientaciones en el marco actual para el desarrollo ...
Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia
(Springer Nature, 2020-03)
Identification of genomic and epigenomic determinants of drug resistance provides important insights for improving cancer treatment. Using agnostic genome-wide interrogation of mRNA and miRNA expression, DNA methylation, ...
Automated procedure to detect subtle motor alterations in the balance beam test in a mouse model of early Parkinson’s disease
(Nature, 2024)
Parkinson’s disease (PD) is the most common motor neurodegenerative disorder, characterised by aggregated α-synuclein (α-syn) constituting Lewy bodies. We aimed to investigate temporal changes in motor impairments in a PD ...
Multicoverage Study of Femtosecond Laser-Induced Desorption of CO from Pd(111)
(ACS, 2024-02)
We study the strong coverage dependence of the femtosecond laser-induced desorption of CO from Pd(111) using molecular dynamics simulations that consistently include the effect of the laser-induced hot electrons on both ...
Synthesis of Waterborne Anticorrosive Coatings Based on The Incorporation of Phosphate Groups to Polyurethane-Acrylate Hybrids
(Wiley, 2023-08)
In this work, solvent-free waterborne polyurethane-poly(meth)acrylate hybrid dispersions that can be used to formulate anticorrosive paints are synthesized. To achieve the anticorrosive protection, a phosphate containing ...
Variants in the 14q32 miRNA cluster are associated with osteosarcoma risk in the Spanish population
(Nature Publishing, 2018-10-18)
Association studies in osteosarcoma risk found significant results in intergenic regions, suggesting that regions which do not codify for proteins could play an important role. The deregulation of microRNAs (miRNAs) has ...
Conjugative Coupling Proteins and the Role of Their Domains in Conjugation, Secondary Structure and in vivo Subcellular Location
(Frontiers Media, 2020-08-11)
Type IV Coupling Proteins (T4CPs) are essential elements in many type IV secretion systems (T4SSs). The members of this family display sequence, length, and domain architecture heterogeneity, being the conserved ...
Extension and improvement of synchronous linear generator based point absorber operation in high wave excitation scenarios
(Elsevier, 2021-11-01)
[EN]The exploitation of marine wave energy resource has led to the design of numerous Wave Energy Converter (WEC) configurations. The power absorption of a WEC is tightly related to its physical properties and the ...
Truncation-Driven Lateral Association of α-Synuclein Hinders Amyloid Clearance by the Hsp70-Based Disaggregase
(MDPI, 2021-11-30)
The aggregation of α-synuclein is the hallmark of a collective of neurodegenerative disorders known as synucleinopathies. The tendency to aggregate of this protein, the toxicity of its aggregation intermediates and the ...