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Mostrando ítems 10741-10750 de 10870
The relevance of Rivendell’s growing cultural value from "The Hobbit to The Lord of the Rings"
(Taylor & Francis, 2023-05-26)
The attention to detail J. R. R. Tolkien showcased in medieval scholarship, widely recognized for its influence on the discipline,Footnote1 did not diminish in his fictional writings. In the sequel to The Hobbit (H, 1937), ...
20 años de la AJIHLE. Historiografía lingüística
(Editorial Universidad de Sevilla, 2021)
[ES] La relevancia de los estudios dedicados a la historiografía lingüística, disciplina que abarca diversas perspectivas y aproximaciones al estudio histórico de las ciencias del lenguaje y del pensamiento lingüístico, ...
Rol de autoridad y análisis del discurso en torno al cáncer de mama en las comunidades de YouTube
(Profesional de la Información, 2024-07-15)
Este artículo forma parte de una reciente línea de investigación surgida tras el diagnóstico y superación de un cáncer de mama por parte de una de las personas que firman este texto académico. En él se aborda, mediante la ...
Use of first-hand data to construct knowledge about the Sun-Earth-Moon system
(Scientia Socialis, 2016-06)
Inquiry-based educational contexts including observation of the Moon have been found to facilitate students´ understanding of the Sun-Earth-Moon system. However, the role that the collected data play in the knowledge ...
El lenguaje en acción: apuntes sobre el diccionario escolar de Juan Benejam (1846-1922)
(Instituto de Língua Portuguesa do Liceu Literário Português, 2021-06-06)
[ES] El maestro Juan Benejam Vives (1846-1922), figura relevante en el entorno educativo menorquín de finales del siglo XIX y principios del XX, fue autor de El lenguaje en acción. Diccionario que comprende la mayor parte ...
Genetics of Type III Bartter Syndrome in Spain, Proposed Diagnostic Algorithm
(Public Library of Science, 2013-09-18)
The p.Ala204Thr mutation (exon 7) of the CLCNKB gene is a "founder" mutation that causes most of type III Bartter syndrome cases in Spain. We performed genetic analysis of the CLCNKB gene, which encodes for the chloride ...
Detailed dissection of UBE3A-mediated DDI1 ubiquitination.
(Frontiers, 2019-05-03)
The ubiquitin E3 ligase UBE3A has been widely reported to interact with the proteasome, but it is still unclear how this enzyme regulates by ubiquitination the different proteasomal subunits. The proteasome receptor DDI1 ...
Rigidified Bis(sulfonyl)ethylenes as Effective Michael Acceptors for Asymmetric Catalysis: Application to the Enantioselective Synthesis of Quaternary Hydantoins
(ACS, 2023-01-11)
The catalytic, enantio- and diastereoselective addition of
hydantoin surrogates II to “rigidified” vinylidene bis(sulfone) reagents is
developed, thus overcoming the inability of commonly employed β-
substituted vinylic ...
Brønsted Base-Catalyzed Enantioselective α-Functionalization of Carbonyl Compounds Involving π-Extended Enolates
(Wiley, 2023-11)
Chiral Brønsted base (BB) catalyzed asymmetric transformations constitute an important tool for synthesis. A meaningful fraction of these transformations proceeds through transiently generated enolate intermediates, which ...
alpha-Branched Ketone Dienolates: Base-Catalyzed Generation and Regio- and Enantioselective Addition Reactions
(Wiley-VCH, 2019-05-14)
In this study, the unique capacity of bifunctional Brønsted bases to generate α-branched ketone dienolates and control both site- and stereoselectivity of their addition reactions to representative classes of carbon ...