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Impact of augmented renal clearance on the pharmacokinetics of linezolid: Advantages of continuous infusion from a pharmacokinetic/pharmacodynamic perspective
(Elsevier, 2020-04)
Objectives: The aim of this study was to assess the influence of renal function, in particular the presence of augmented renal clearance (ARC), on the pharmacokinetics of linezolid in critically ill patients. The effect ...
Novel Population Pharmacokinetic Model for Linezolid in Critically Ill Patients and Evaluation of the Adequacy of the Current Dosing Recommendation
(MDPI, 2020-01-09)
Antimicrobial treatment in critically ill patients remains challenging. The aim of this study
was to develop a population pharmacokinetic model for linezolid in critically ill patients and to
evaluate the adequacy of ...