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Palladium-Catalyzed Dehydrogenative Coupling: An Efficient Synthetic Strategy for the Construction of the Quinoline Core
(MDPI, 2017-09)
Palladium-catalyzed dehydrogenative coupling is an efficient synthetic strategy for the construction of quinoline scaffolds, a privileged structure and prevalent motif in many natural and biologically active products, in ...
Phenolic Activation in Chiral Brønsted Acid-Catalyzed Intramolecular α‑Amidoalkylation Reactions for the Synthesis of Fused Isoquinolines
(ACS, 2017-06-16)
An organolithium addition−intramolecular α-
amidoalkylation sequence on N-phenethylimides has been
developed for the synthesis of fused tetrahydroisoquinoline
systems using 1,1′-bi-2-naphthol (binol)-derived Brønsted
acids. ...
Intramolecular Addition of Heteroaryllithiums onto Activated Alkenes. Access to Heterofused Indolizines and Pyrroloazepines
(Wiley, 2017-02-23)
Heteroaryllithiums, obtained via MesLi mediated halogen- lithium exchange, undergo intramolecular addition onto acrylamide and acrylate moieties. Both electron rich (thiophenyl) and electron deficient (pyridinyl, quinolinyl) ...