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Use of Recombinant Antigens for the Diagnosis of Invasive Candidiasis
(Hindawi Publishing Corporation, 2008)
Invasive candidiasis is a frequent and often fatal complication in immunocompromised and critically ill patients. Unfortunately, the diagnosis of invasive candidiasis remains difficult due to the lack of specific clinical ...
Antibacterial and antifungal activity of the human endometrial fluid during the natural cycle
(Hindawi, 2021-06-16)
[EN] Purpose. Some microbiota patterns have been associated with favorable IVF prognosis and others with pathological conditions. The
endometrial fluid aspirate (EFA) contains antibacterial proteins that are enriched in ...
Diagnosis of invasive candidiasis by enzyme-linked immunosorbent assay using the N-terminal fragment of Candida albicans hyphal wall protein I
(BioMed Central, 2007-04)
Background: The diagnosis of invasive candidiasis is difficult because there are no specific clinical manifestations of the disease and colonization and infection are difficult to distinguish. In the last decade, much ...
Antibody Complementarity-Determining Regions (CDRs) Can Display Differential Antimicrobial, Antiviral and Antitumor Activities
(Public Library of Science, 2008-06-11)
Background: Complementarity-determining regions (CDRs) are immunoglobulin (Ig) hypervariable domains that determine specific antibody (Ab) binding. We have shown that synthetic CDR-related peptides and many decapeptides ...
Humoral Immunity Links Candida albicans Infection and Celiac Disease
(Public Library of Science, 2015-03-20)
Objective
The protein Hwp1, expressed on the pathogenic phase of Candida albicans, presents sequence analogy with the gluten protein gliadin and is also a substrate for transglutaminase. This had led to the suggestion ...
Biomarkers for the diagnosis of invasive candidiasis in immunocompetent and immunocompromised patients
(Elsevier, 2021-07-24)
Blood culture methods show low sensitivity, so reliable non-culture diagnostic tests are needed to help clinicians with the introduction, de-escalation, and discontinuation of antifungal therapy in patients with suspected ...
Low Sensitivity of Conventional Fungal Agars in Fungemia by Rhodotorula Mucilaginosa: Description of Two Cases
(BioMed Central, 2021-03-27)
Background Although most bloodstream yeast infections are caused by Candida spp., infections by rare or less common species have increased in recent years. Diagnosis of infections caused by these species is difficult due ...
Anti-Candida Antibodies of Patients with Invasive Candidiasis Inhibit Growth, Alter Cell Wall Structure, and Kill Candida albicans In Vitro
(Springer Nature, 2024)
Invasive candidiasis (IC), caused by Candida yeasts, particularly Candida albicans, poses a significant threat with high mortality rates. Diagnosis is challenging due to Candida's common presence in human microbiota. To ...