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Global Self-Organization of the Cellular Metabolic Structure
(Public Library Science, 2008-08)
Background: Over many years, it has been assumed that enzymes work either in an isolated way, or organized in small catalytic groups. Several studies performed using "metabolic networks models'' are helping to understand ...
Contribution of Pannexin1 to Experimental Autoimmune Encephalomyelitis
(Public Library of Science, 2013-06)
Pannexin1 (Panx1) is a plasma membrane channel permeable to relatively large molecules, such as ATP. In the central nervous system (CNS) Panx1 is found in neurons and glia and in the immune system in macrophages and T-cells. ...
Global Self-Regulation of the Cellular Metabolic Structure
(Public Library of Science, 2010-03-02)
Background: Different studies have shown that cellular enzymatic activities are able to self-organize spontaneously, forming a metabolic core of reactive processes that remain active under different growth conditions while ...