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Fine-Tuning of Sirtuin 1 Expression Is Essential to Protect the Liver From Cholestatic Liver Disease
(Wiley, 2019-02)
Cholestasis comprises aetiologically heterogeneous conditions characterized by accumulation of bile acids in the liver that actively contribute to liver damage. Sirtuin 1 (SIRT1) regulates liver regeneration and bile acid ...
Infective endocarditis in hypertrophic cardiomyopathy A multicenter, prospective, cohort study
(Lippincott Williams & Wilkins, 2016-06)
Infective endocarditis (IE) complicating hypertrophic cardiomyopathy (HCM) is a poorly known entity. Although current guidelines do not recommend IE antibiotic prophylaxis (IEAP) in HCM, controversy remains.This study ...
Tropheryma whipplei endocarditis in Spain Case: reports of 17 prospective cases
(Lippincott Williams & Wilkins, 2016-06)
Tropheryma whipplei endocarditis is an uncommon condition with very few series and <90 cases reported in the literature. The aim of the study was to analyze the epidemiological, clinical, and outcome characteristics of 17 ...
Extracellular Vesicles in Liver Diseases: Meeting Report from the International Liver Congress 2018
(Wiley, 2019-02)
Extracellular vesicles (EVs) are small and heterogeneous membrane-bound structures released by cells and found in all biological fluids. They are effective intercellular communicators, acting on a number of close and/or ...
Mediterranean diet and quality of life: Baseline cross-sectional analysis of the PREDIMED-PLUS trial
(Public Libray fo Science, 2018-06-18)
We assessed if a 17-item score capturing adherence to a traditional Mediterranean diet (MedDiet) was associated with better health-related quality of life among older Spanish men and women with overweight or obesity harboring ...
Adaptive Downregulation of Cl-/HCO3- Exchange Activity in Rat Hepatocytes under Experimental Obstructive Cholestasis
(Public Library Science, 2019-02-21)
In obstructive cholestasis, there is an integral adaptive response aimed to diminish the bile flow and minimize the injury of bile ducts caused by increased intraluminal pressure and harmful levels of bile salts and ...
Burkitt-like lymphoma with 11q aberration: a germinal center-derived lymphoma genetically unrelated to Burkitt lymphoma
(Ferrata Storti Foundation, 2019-08-31)
Burkitt-like lymphoma with 11q aberration is characterized by pathological features and gene expression profile resembling those of Burkitt lymphoma but lacks the MYC rearrangement and carries an 11q-arm aberration with ...
Influence of MUC5B gene on antisynthetase syndrome
(Nature, 2020-01-29)
MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
Influence of MUC5B gene on antisynthetase syndrome
(Nature, 2020-01-29)
MUC5B rs35705950 (G/T) is strongly associated with idiopathic pulmonary fibrosis (IPF) and also contributes to the risk of interstitial lung disease (ILD) in rheumatoid arthritis (RA-ILD) and chronic hypersensitivity ...
Hole-in-one: simple non-surgical technique for the management of anterior chamber migrated Ozurdex implant
(GMS, 2020-02-27)
Introduction: The migration of a dexamethasone implant to the anterior chamber is a vision-threatening complication which can happen in non-compartmentalized eyes treated with this device. Previous literature suggests that ...