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Detection of Atomic Scale Changes in the Free Volume Void Size of Three-Dimensional Colorectal Cancer Cell Culture Using Positron Annihilation Lifetime Spectroscopy
(Public Library of Science, 2014-01-02)
Positron annihilation lifetime spectroscopy (PALS) provides a direct measurement of the free volume void sizes in polymers and biological systems. This free volume is critical in explaining and understanding physical and ...
Executing SADI services in Galaxy
(Biomed Central, 2014-09-22)
Background: In recent years Galaxy has become a popular workflow management system in bioinformatics, due to its ease of installation, use and extension. The availability of Semantic Web-oriented tools in Galaxy, however, ...
Automatically exposing OpenLifeData via SADI semantic Web Services
(Biomed Central, 2014-11-19)
Background: Two distinct trends are emerging with respect to how data is shared, collected, and analyzed within the bioinformatics community. First, Linked Data, exposed as SPARQL endpoints, promises to make data easier ...
Celiac disease in the Mediterranean area
(BioMed Central, 2014-02)
Background: The World Gastroenterology Organization recommends developing national guidelines for the diagnosis of Celiac Disease (CD): hence a profile of the diagnosis of CD in each country is required. We aim to describe ...
Involvement of ANXA5 and ILKAP in Susceptibility to Malignant Melanoma
(Public Library Science, 2014-04-17)
Single nucleotide-polymorphisms (SNPs) are a source of diversity among human population, which may be responsible for the different individual susceptibility to diseases and/or response to drugs, among other phenotypic ...
The Interplay between Natural Selection and Susceptibility to Melanoma on Allele 374F of SLC45A2 Gene in a South European Population
(Public Library Science, 2014-08-05)
We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population ...
The E2F2 Transcription Factor Sustains Hepatic Glycerophospholipid Homeostasis in Mice
(Public Library Science, 2014-11-14)
Increasing evidence links metabolic signals to cell proliferation, but the molecular wiring that connects the two core machineries remains largely unknown. E2Fs are master regulators of cellular proliferation. We have ...
The Carpathian range represents a weak genetic barrier in South-East Europe
(Biomed Central, 2014-05-15)
Background: In the present study we have assessed whether the Carpathian Mountains represent a genetic barrier in East Europe. Therefore, we have analyzed the mtDNA of 128 native individuals of Romania: 62 of them from the ...
Macrozooplankton predation impact on anchovy (Engraulis encrasicolus) eggs mortality at the Bay of Biscay shelf break spawning centre
(Oxford University Press, 2014-11-23)
A real-time PCR based method involving a species-specific probe was applied to detect Engraulis encrasicolus eggs predation by the macrozooplank-
ton community during the 2011 spawning season. Three locations along the ...
A real-time PCR assay to estimate invertebrate and fish predation on anchovy eggs in the Bay of Biscay
(Elsevier, 2014-12-12)
In order to investigate the role of predation on eggs and larvae in the recruitment of anchovy (Engraulis encrasicolus), sardine (Sardina pilchardus), sprat (Sprattus sprattus) and 52 macrozooplankton taxa were assayed for ...