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m6A Methylated Long Noncoding RNA LOC339803 Regulates Intestinal Inflammatory Response
(Wiley, 2024-04)
Cytokine mediated sustained inflammation increases the risk to develop different complex chronic inflammatory diseases, but the implicated mechanisms remain unclear. Increasing evidence shows that long noncoding RNAs ...
CircRNAome of Childhood Acute Lymphoblastic Leukemia: Deciphering Subtype-Specific Expression Profiles and Involvement in TCF3::PBX1 ALL
(MDPI, 2024-01-25)
Childhood B-cell acute lymphoblastic leukemia (B-ALL) is a heterogeneous disease comprising multiple molecular subgroups with subtype-specific expression profiles. Recently, a new type of ncRNA, termed circular RNA (circRNA), ...
Evaluation of Various Types of Alginate Inks for Light-Mediated Extrusion 3D Printing
(MDPI, 2024-04-04)
Naturally derived biopolymers modifying or combining with other components are excellent candidates to promote the full potential of additive manufacturing in biomedicine, cosmetics, and the food industry. This work aims ...
Extrusion-Based 3D Printing of Photocrosslinkable Chitosan Inks
(MDPI, 2024-02-04)
Photocuring of chitosan has shown great promise in the extrusion-based 3D printing of scaffolds for advanced biomedical and tissue engineering applications. However, the poor mechanical stability of methacrylated chitosan ...
Membrane Interaction Characteristics of the RTX Toxins and the Cholesterol-Dependence of Their Cytolytic/Cytotoxic Activity
(MDPI, 2024-03-08)
RTX toxins are important virulence factors produced by a wide range of Gram-negative bacteria. They are secreted as water-soluble proteins that are able to bind to the host cell membrane and insert hydrophobic segments ...
The Influence of Lipid Electric Charge on the Binding of Aβ(1–42) Amyloid Peptide to Bilayers in the Liquid-Ordered State
(MDPI, 2024-03-01)
The amyloidogenic Aβ peptides are widely considered as a pathogenic agent in Alzheimer’s disease. Aβ(1-42) would form aggregates of amyloid fibrils on the neuron plasma membranes, thus perturbing neuronal functionality. ...
Allosteric control of dynamin-related protein 1 through a disordered C-terminal Short Linear Motif
(Nature, 2024-01)
The mechanochemical GTPase dynamin-related protein 1 (Drp1) catalyzes mitochondrial and peroxisomal fission, but the regulatory mechanisms remain ambiguous. Here we find that a conserved, intrinsically disordered, six-residue ...
Improving the mechanical and biological functions of cell sheet constructs: The interplay of human-derived periodontal ligament stem cells, endothelial cells and plasma rich in growth factors
(Elsevier, 2024-05)
Objective
The aim of this study was to produce and characterize triple-layered cell sheet constructs with varying cell compositions combined or not with the fibrin membrane scaffold obtained by the technology of Plasma ...
On the antimicrobial properties and endurance of eugenol and 2-phenylphenol functionalized sol-gel coatings
(Elsevier, 2024-04)
Preventing microbiological surface contamination in public spaces is nowadays of high priority. The proliferation of a microbial infection may arise through air, water, or direct contact with infected surfaces. Chemical ...
Enhanced phytoremediation of metal contaminated soils aimed at decreasing the risk of antibiotic resistance dissemination
(Frontiers Media, 2024)
The enhanced phytoremediation of metal contaminated soils holds great
promise for the recovery of soil health and functionality, while providing a
range of co-benefits, from an environmental and human health perspectiv ...