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Two Nuclear Localization Signals in USP1 Mediate Nuclear Import of the USP1/UAF1 Complex

García Santisteban, Iraia; Zorroza, Kerman; Rodríguez Pérez, José Antonio (Public Library of Science, 2012-06-06)

The human deubiquitinase USP1 plays important roles in cancer-related processes, such as the DNA damage response, and the maintenance of the undifferentiated state of osteosarcoma cells. USP1 deubiquitinase activity is ...

Multiple SNP Markers Reveal Fine-Scale Population and Deep Phylogeographic Structure in European Anchovy (Engraulis encrasicolus L.)

Zarraonaindia Martínez, Iratxe; Iriondo Orensanz, Mikel; Albaina Vivanco, Aitor; Pardo, Muguel Ángel; Manzano Basabe, Carmen; Grant, W. Stewart; Irigoien, Xabier; Estomba Recalde, Miren Andone (Public Library of Science, 2012-07-30)

Geographic surveys of allozymes, microsatellites, nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) have detected several genetic subdivisions among European anchovy populations. However, these studies have been limited in ...

Ancient DNA from Hunter-Gatherer and Farmer Groups from Northern Spain Supports a Random Dispersion Model for the Neolithic Expansion into Europe

Hervella Afonso, Montserrat; Izagirre Arribalzaga, Neskuts; Alonso Alegre, Santos; Fregel, Rosa; Alonso, Antonio; Cabrera, Vicente M.; De la Rúa Vaca, Concepción (Public Library of Science, 2012-04-25)

Background/Principal Findings: The phenomenon of Neolithisation refers to the transition of prehistoric populations from a hunter-gatherer to an agro-pastoralist lifestyle. Traditionally, the spread of an agro-pastoralist ...

PAnalyzer: A software tool for protein inference in shotgun proteomics

Prieto Agujeta, Gorka; Aloria Escolastico, Kerman; Osinalde Moraleja, Nerea; Fullaondo Elordui-Zapaterieche, Asier; Arizmendi Bastarrika, Jesús María; Matthiesen, Rune (BioMed Central, 2012-11-05)

Background Protein inference from peptide identifications in shotgun proteomics must deal with ambiguities that arise due to the presence of peptides shared between different proteins, which is common in higher eukaryotes. ...