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Selective Interaction of Syntaxin 1A with KCNQ2: Possible Implications for Specific Modulation of Presynaptic Activity
(Public Library Science,, 2009-08-13)
KCNQ2/KCNQ3 channels are the molecular correlates of the neuronal M-channels, which play a major role in the control of neuronal excitability. Notably, they differ from homomeric KCNQ2 channels in their distribution pattern ...
Glycosaminoglycans in human retinoblastoma cells: heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactions
(BioMed Central, 2003-02-19)
BACKGROUND: Pigment epithelium-derived factor (PEDF) has binding affinity for cell-surface receptors in retinoblastoma cells and for glycosaminoglycans. We investigated the effects of glycosaminoglycans on PEDF-receptor ...
A Computational Analysis of Protein-Protein Interaction Networks in Neurodegenerative Diseases
(Biomed Central, 2008-06-20)
Background: Recent developments have meant that network theory is making an important contribution to the topological study of biological networks, such as protein-protein interaction (PPI) networks. The identification of ...
Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis
(BioMed Central, 2008-10)
Background: The recruitment of vascular stromal and endothelial cells is an early event occurring during cancer cell growth at premetastatic niches, but how the microenvironment created by the initial three-dimensional ...
Phosphorylation of the carboxy-terminal domain of histone H1: effects on secondary structure and DNA condensation
(Oxford University Press, 2008-08)
Linker histone H1 plays an important role in chromatin folding. Phosphorylation by cyclin-dependent kinases is the main post-translational modification of histone H1. We studied the effects of phosphorylation on the secondary ...
A Self-Referencing Intensity Based Polymer Optical Fiber Sensor for Liquid Detection
(MDPI, 2009-08)
A novel self-referencing fiber optic intensity sensor based on bending losses of a partially polished polymer optical fiber (POF) coupler is presented. The coupling ratio (K) depends on the external liquid in which the ...
Asymptotic Comparison of the Solutions of Linear Time-Delay Systems with Point and Distributed Lags with Those of Their Limiting Equations
(Hindawi Publishing Corporation, 2009)
This paper investigates the relations between the particular eigensolutions of a limiting functional differential equation of any order, which is the nominal (unperturbed) linear autonomous differential equations, and the ...
On the uniform exponential stability of linear time-delay systems
(Hindawi Publishing Corporation, 2004)
This paper deals with the global uniform exponential stability independent of delay of time-delay linear and time-invariant systems subject to point and distributed delays for the initial conditions being continuous real ...
New Uses for Old Needs in the Diaspora: Watching Basque Television in Latin America
(Macquarie University, 2006)
The transformations occurring in the communications media are resulting in the emergence of new uses amongst diasporic and migratory groups. An example of this is found in satellite television, which makes the regular, ...
Geolinguistic Regions and Diasporas in the Age of Satellite Television
(SAGE Publications, 2007)
Studies of the globalization processes in the communications media have frequently emphasized the planetary-scale diffusion of the dominant cultural and linguistic models. This is undoubtedly a clearly observable tendency ...