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The Oxidative State of Chylomicron Remnants Influences Their Modulation of Human Monocyte Activation
(Hindawi Publishing Corporation, 2012)
Chylomicron remnants (CMRs) contribute directly to human monocyte activation in vitro, by increasing reactive oxygen species (ROS) production and cell migration. In this study, the effects of the oxidative state of CMR on ...
Wide Screening of Phage-Displayed Libraries Identifies Immune Targets in Planta
(PLoS ONE, 2013)
Microbe-Associated Molecular Patterns and virulence effectors are recognized by plants as a first step to mount a defence response against potential pathogens. This recognition involves a large family of extracellular ...
Physiological modules for generating discrete and rhythmic movements: action identification by a dynamic recurrent neural network
(Frontiers Research Foundation, 2014-09-17)
In this study we employed a dynamic recurrent neural network (DRNN) in a novel fashion to reveal characteristics of control modules underlying the generation of muscle activations when drawing figures with the outstretched ...
Physiological modules for generating discrete and rhythmic movements: Component analysis of EMG signals
(Frontiers Research Foundation, 2015-01-09)
A central question in Neuroscience is that of how the nervous system generates the spatiotemporal commands needed to realize complex gestures, such as handwriting. A key postulate is that the central nervous system (CNS) ...
Allostatic hypermetabolic response in PGC1 alpha/beta heterozygote mouse despite mitochondrial defects
(Wiley, 2021-09)
Aging, obesity, and insulin resistance are associated with low levels of PGC1 alpha and PGC1 beta coactivators and defective mitochondrial function. We studied mice deficient for PGC1 alpha and PGC1 beta [double heterozygous ...
Genetics of Somatotype and Physical Fitness in Children and Adolescents
(Wiley, 2021-05)
Objectives To analyze the influence of genetic and environmental factors on the variation in somatotype, physical fitness, and their mutual associations. Methods Twins from 214 pairs (87 monozygotic) of the Autonomous ...
Hepatokines and adipokines in NASH-related hepatocellular carcinoma
(Elsevier, 2020-11-05)
Summary
The incidence of hepatocellular carcinoma (HCC) is increasing in industrialised societies; this is likely
secondary to the increasing burden of non-alcoholic fatty liver disease (NAFLD), its progressive form ...
Systematic analysis of chemical-protein interactions from zebrafish embryo by proteome-wide thermal shift assay, bridging the gap between molecular interactions and toxicity pathways
(Elsevier, 2021-10-30)
[EN]The molecular interaction between chemicals and proteins often promotes alteration of cellular function. One of the challenges of the toxicology is to predict the impact of exposure to chemicals. Assessing the impact ...
Anti-TNFα treatment in Crohn’s disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status
(Wiley, 2021-11)
Background and Aims An association between Crohn's disease (CD) and hepatic steatosis has been reported. However, the underlying mechanisms of steatosis progression in CD are not clear. Among the most effective CD treatments ...