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Role of Monoubiquitylation on the Control of IκBα Degradation and NF-κB Activity
(Public Library of Science, 2011-10-12)
The NF-κB pathway is regulated by multiple post-translational modifications including phosphorylation, ubiquitylation and SUMOylation. Many of these modifications act on the natural inhibitor IκBα modulating its capacity ...
FTY720 attenuates excitotoxicity and neuroinflammation
(BioMed Central, 2015-05-08)
Background: FTY720 (fingolimod, Gilenya(TM)), a structural analog of sphingosine-1-phosphate (S1P), is the first oral drug approved for treatment the relapsing-remitting form of multiple sclerosis (MS), and its efficacy ...
Los requisitos para acceder a las magistraturas locales con base en los escritos de los juristas clásicos
(Servicio Editorial de la Universidad del País Vasco/Euskal Herriko Unibertsitateko Argitalpen Zerbitzua, 2011)
[ES] El artículo analiza los requisitos requeridos, avanzado el Principado, para
ser magistrado local, con base en la información proporcionada por los escritos de los juristas, en particular de los conocidos como clásicos ...
Humoral Immunity Links Candida albicans Infection and Celiac Disease
(Public Library of Science, 2015-03-20)
Objective
The protein Hwp1, expressed on the pathogenic phase of Candida albicans, presents sequence analogy with the gluten protein gliadin and is also a substrate for transglutaminase. This had led to the suggestion ...
Double layers in gravity theories
(IOP Publishing, 2015)
Gravitational double layers, unlike their classical electromagnetic counterparts, are thought to be forbidden in gravity theories. It has been recently shown, however, that they are feasible in, for instance, gravity ...
Nuevos alimentos: la percepción del consumidor
(Fundación Española de Dietistas-Nutricionistas (FEDN), 2011)
Se analizan tres alimentos funcionales: el yogur Activia, las bebidas con fitoesteroles, y la leche enriquecida con calcio. Para cada uno de ellos interesa conocer: la frecuencia de consumo, las razones para consumirlos, ...
Reduced antioxidant defense in early onset first-episode psychosis: a case-control study
(BioMed Cental, 2011)
Background
Our objective is to determine the activity of the antioxidant defense system at admission in patients with early onset first psychotic episodes compared with a control group.
Methods
Total antioxidant status ...
Faculty Preferences for Training Modalities on ICTs
(Universidad del País Vasco / Euskal Herriko Unibertsitatea, 2011)
[En] The goal of this research is twofold: firstly, to identify the possible differences in faculty's attitudes toward and use of new technological resources; and secondly, to identify the educational interaction established ...
Influence of the conductor temperature error on the overhead line ampacity monitoring systems
(The Institution of Engineering and Technology, 2011-04)
Many real time overhead line ampacity monitoring systems are based on the calculation of the wind speed. The wind speed is obtained from the conductor temperature. The conductor temperature can be measured directly or it ...
Mechanisms of action of Methylthioadenosine: pathways implicated in neuroprotection in models of Multiple Sclerosis and other neurological diseases
(BioMed Central, 2010-11-25)
Background
Methylthioadenosine (MTA) has anti-oxidant and anti-proliferative properties and was shown to induce cell protection in hepatic cells. We previously demonstrated that exert immunomodulatory and neuroprotective ...