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Polyether Synthesis by Bulk Self-Condensation of Diols Catalyzed by Non-eutectic Acid Base Organocatalysts
(American Chemical Society, 2019-01-25)
Polyethers constitute a well-established class of polymers covering a wide range of applications from industrial man-ufacturing to nanomedicine. Nevertheless, their industrial implementation is limited to short chain ...
Association Between Medication Adherence and Oxidative Stress in Patients With First-Episode Mania
(Frontiers Media, 2019-03-26)
Poor adherence is a major problem in patients with manic episodes that impairs functionality and has unknown effects on oxidative stress. The objective of this study was to analyze the relationship between adherence to ...
Charge transport modulation in pseudorotaxane 1D stacks of acene and azaacene derivatives
(Royal Society of Chemistry, 2019-03-07)
Acenes have received a lot of attention because of their inherent and tunable absorbing, emissive, and charge transport properties for electronic, photovoltaic, and singlet fission applications, among others. Such properties ...
Functional Analysis of LDLR (Low-Density Lipoprotein Receptor) Variants in Patient Lymphocytes to Assess the Effect of Evinacumab in Homozygous Familial Hypercholesterolemia Patients With a Spectrum of LDLR Activity
(Lippincott Williams & Wilkins, 2019-10-03)
Objective: Homozygous familial hypercholesterolemia is a rare disease usually caused by LDLR (low-density lipoprotein receptor) mutations. Homozygous familial hypercholesterolemia is characterized by markedly elevated LDL-C ...
3D Scaffolds Based on Conductive Polymers for Biomedical Applications
(ACS Publications, 2019-01-14)
3D scaffolds appear to be a cost-effective ultimate answer
for biomedical applications, facilitating rapid results while providing an
environment similar to in vivo tissue. These biomaterials offer large
surface areas ...
Innovative Electrolytes Based on Ionic Liquids and Polymers for Next-Generation Solid-State Batteries
(ACS, 2019-02-25)
Electrolytes based on organic solvents used in current Li-ion batteries are not compatible with the next-generation energy storage technologies including those based on Li metal. Thus, there has been an increase in research ...
Environmental factors modulated ancient mitochondrial DnA variability and the prevalence of rheumatic diseases in the Basque country
(Nature, 2019-12-31)
Among the factors that would explain the distribution of mitochondrial lineages in Europe, climate and diseases may have played an important role. A possible explanation lies in the nature of the mitochondrion, in which ...
Environmental enrichment shapes striatal spike-timing-dependent plasticity in vivo
(Nature, 2019-12-19)
Behavioural experience, such as environmental enrichment (EE), induces long-term effects on learning and memory. Learning can be assessed with the Hebbian paradigm, such as spike-timing-dependent plasticity (STDP), which ...
Microstructural control suppresses thermal activation of electron transport at room temperature in polymer transistors
(Nature Publishing Group, 2019-07-29)
Recent demonstrations of inverted thermal activation of charge mobility in polymer field-effect transistors have excited the interest in transport regimes not limited by thermal barriers. However, rationalization of the ...
The MAPT H1 Haplotype Is a Risk Factor for Alzheimer’s Disease in APOE ε4 Non-carriers
(Frontiers Media, 2019-12-04)
An ancestral inversion of 900 kb on chromosome 17q21, which includes the microtubule-associated protein tau (MAPT) gene, defines two haplotype clades in Caucasians (H1 and H2). The H1 haplotype has been linked inconsistently ...