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dc.contributor.authorMilton Laskibar, Iñaki
dc.contributor.authorGómez Zorita, Saioa
dc.contributor.authorAguirre López, Leixuri ORCID
dc.contributor.authorFernández Quintela, Alfredo ORCID
dc.contributor.authorGonzález, Marcela
dc.contributor.authorPortillo Baquedano, María Puy ORCID
dc.date.accessioned2019-01-08T19:14:18Z
dc.date.available2019-01-08T19:14:18Z
dc.date.issued2017-11-29
dc.identifier.citationMolecules 22(12) : (2017) // Article ID 2091es_ES
dc.identifier.issn1420-3049
dc.identifier.urihttp://hdl.handle.net/10810/30675
dc.description.abstractScience constantly seeks to identify new molecules that could be used as dietary functional ingredients in the fight against obesity and its co-morbidities. Among them, polyphenols represent a group of molecules of increasing interest. One of the most widely studied polyphenols is resveratrol (trans-3,4′,5-trihydroxystilbene), which has been proposed as an “energy restriction mimetic” because it can exert energy restriction-like effects. The aim of this review is to analyze the effects of resveratrol on obesity under different feeding conditions, such as overfeeding, normal feeding, and energy restriction, in animals and humans. The vast majority of the studies reported have addressed the administration of resveratrol to animals alongside an obesogenic diet. Under these experimental conditions usually a decreased body weight amount was found. To date, studies that focus on the effects of resveratrol under normal feeding or energy restriction conditions in animals and humans are scarcer. In these studies no changes in body fat were reported. After analyzing the results obtained under overfeeding, normal feeding, and energy restriction conditions, it can be stated that resveratrol is useful in reducing body fat accumulation, and thus preventing obesity. Nevertheless, for ethical reasons, these results have been obtained in animals. By contrast, there are no evidences showing the usefulness of this phenolic compound in reducing previously accumulated body fat. Consequently, as of yet, there is not scientific support for proposing resveratrol as a new anti-obesity treatment tool.es_ES
dc.description.sponsorshipThis work has been supported by MINECO (AGL-2015-65719-R-MINECO/FEDER, UE), Fondo Europeo de Desarrollo Regional (FEDER) University of the Basque Country (ELDUNANOTEK UFI11/32), Instituto de Salud Carlos III (CIBEROBN) and Basque Government (IT-572-13). Inaki Milton is a recipient of a doctoral fellowship from the Basque Government.es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.relationinfo:eu-repo/grantAgreement/MINECO/AGL-2015-65719-Res_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectresveratroles_ES
dc.subjectnormal feedinges_ES
dc.subjectoverfeedinges_ES
dc.subjectenergy restrictiones_ES
dc.subjectrodentses_ES
dc.subjecthumanes_ES
dc.titleResveratrol-Induced Effects on Body Fat Differ Depending on Feeding Conditionses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holder© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).es_ES
dc.rights.holderAtribución 3.0 España*
dc.relation.publisherversionhttps://www.mdpi.com/1420-3049/22/12/2091es_ES
dc.identifier.doi10.3390/molecules22122091
dc.departamentoesFarmacia y ciencias de los alimentoses_ES
dc.departamentoeuFarmazia eta elikagaien zientziakes_ES


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© 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Except where otherwise noted, this item's license is described as © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).