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dc.contributor.authorBogl, Leonie H
dc.contributor.authorJelenkovic Moreno, Aline
dc.contributor.authorVuoksimaa, Eero
dc.contributor.authorAhrenfeldt, Linda
dc.contributor.authorPietiläinen, Kirsi H.
dc.contributor.authorStazi, Maria A.
dc.contributor.authorFagnani, Corrado
dc.contributor.authorD’Ippolito, Cristina
dc.contributor.authorHur, Yoon-Mi
dc.contributor.authorJeong, Hoe-Uk
dc.contributor.authorSilberg, Judy L.
dc.contributor.authorEaves, Lindon J.
dc.contributor.authorMaes, Hermine H.
dc.contributor.authorBayasgalan, Gombojav
dc.contributor.authorNarandalai, Danshiitsoodol
dc.contributor.authorCutler, Tessa L.
dc.contributor.authorKandler, Christian
dc.contributor.authorJang, Kerry L.
dc.contributor.authorChristensen, Kaare
dc.contributor.authorSkytthe, Axel
dc.contributor.authorKyvik, Kirsten O.
dc.contributor.authorCozen, Wendy
dc.contributor.authorHwang, Amie E.
dc.contributor.authorMack, Thomas M.
dc.contributor.authorDerom, Catherine A.
dc.contributor.authorVlietinck, Robert F.
dc.contributor.authorNelson, Tracy L.
dc.contributor.authorWhitfield, Keith E.
dc.contributor.authorCorley, Robin P.
dc.contributor.authorHuibregtse, Brooke M.
dc.contributor.authorMcAdams, Tom A.
dc.contributor.authorEley, Thalia C.
dc.contributor.authorGregory, Alice M.
dc.contributor.authorKrueger, Robert F.
dc.contributor.authorMcGue, Matt
dc.contributor.authorPahlen, Shandell
dc.contributor.authorWillemsen, Gonneke
dc.contributor.authorBartels, Meike
dc.contributor.authorVan Beijsterveldt, Toos C. E. M.
dc.contributor.authorPang, Zengchang
dc.contributor.authorTan, Qihua
dc.contributor.authorZhang, Dongfeng
dc.contributor.authorMartin, Nicholas G.
dc.contributor.authorMedland, Sarah E.
dc.contributor.authorMontgomery, Grant W.
dc.contributor.authorHjelmborg, Jacob v. B.
dc.contributor.authorRebato Ochoa, Esther Matilde
dc.contributor.authorSwan, Gary E.
dc.contributor.authorKrasnow, Ruth
dc.contributor.authorBusjahn, Andreas
dc.contributor.authorLichtenstein, Paul
dc.contributor.authorÖncel, Sevgi Y.
dc.contributor.authorAliev, Fazil
dc.contributor.authorBaker, Laura A.
dc.contributor.authorTuvblad, Catherine
dc.contributor.authorSiribaddana, Sisira H.
dc.contributor.authorHotopf, Matthew
dc.contributor.authorSumathipala, Athula
dc.contributor.authorRijsdijk, Fruhling
dc.contributor.authorMagnusson, Patrik K. E.
dc.contributor.authorPedersen, Nancy L.
dc.contributor.authorDahl Aslan, Anna K.
dc.contributor.authorOrdoñana, Juan R.
dc.contributor.authorSánchez-Romera, Juan F.
dc.contributor.authorColodro-Conde, Lucia
dc.contributor.authorDuncan, Glen E.
dc.contributor.authorBuchwald, Dedra
dc.contributor.authorTarnoki, Adam D.
dc.contributor.authorTarnoki, David L.
dc.contributor.authorYokoyama, Yoshie
dc.contributor.authorHopper, John L.
dc.contributor.authorLoos, Ruth J. F.
dc.contributor.authorBoomsma, Dorret I.
dc.contributor.authorSørensen, Thorkild I. A.
dc.contributor.authorSilventoinen, Karri
dc.contributor.authorKaprio, Jaakko
dc.date.accessioned2019-04-05T11:45:19Z
dc.date.available2019-04-05T11:45:19Z
dc.date.issued2017-04-27
dc.identifier.citationBiology of Sex Differences 8 : (2017) // Article ID 14es_ES
dc.identifier.issn2042-6410
dc.identifier.urihttp://hdl.handle.net/10810/32354
dc.description.abstractBackground: The comparison of traits in twins from opposite-sex (OS) and same-sex (SS) dizygotic twin pairs is considered a proxy measure of prenatal hormone exposure. To examine possible prenatal hormonal influences on anthropometric traits, we compared mean height, body mass index (BMI), and the prevalence of being overweight or obese between men and women from OS and SS dizygotic twin pairs. Methods: The data were derived from the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) database, and included 68,494 SS and 53,808 OS dizygotic twin individuals above the age of 20 years from 31 twin cohorts representing 19 countries. Zygosity was determined by questionnaires or DNA genotyping depending on the study. Multiple regression and logistic regression models adjusted for cohort, age, and birth year with the twin type as a predictor were carried out to compare height and BMI in twins from OS pairs with those from SS pairs and to calculate the adjusted odds ratios and 95% confidence intervals for being overweight or obese. Results: OS females were, on average, 0.31 cm (95% confidence interval (CI) 0.20, 0.41) taller than SS females. OS males were also, on average, taller than SS males, but this difference was only 0.14 cm (95% CI 0.02, 0.27). Mean BMI and the prevalence of overweight or obesity did not differ between males and females from SS and OS twin pairs. The statistically significant differences between OS and SS twins for height were small and appeared to reflect our large sample size rather than meaningful differences of public health relevance. Conclusions: We found no evidence to support the hypothesis that prenatal hormonal exposure or postnatal socialization (i.e., having grown up with a twin of the opposite sex) has a major impact on height and BMI in adulthood.es_ES
dc.description.sponsorshipThis study was conducted within the CODATwins project (Academy of Finland #266592). The lead author wishes to thank the Juho Vainio Foundation and the Yrjo Jahnsson Foundation. The Australian Twin Registry is supported by a Centre of Research Excellence (grant ID 1079102) from the National Health and Medical Research Council administered by the University of Melbourne. California Twin Program was supported by The California Tobacco-Related Disease Research Program (7RT-0134H, 8RT-0107H, 6RT-0354H) and the National Institutes of Health (1R01ESO15150-01). The Carolina African American Twin Study of Aging (CAATSA) was funded by a grant from the National Institute on Aging (grant 1RO1-AG13662-01A2) to K.E. Whitfield. Colorado Twin Registry is funded by NIDA funded center grant DA011015, and Longitudinal Twin Study HD10333; Author Huibregtse is supported by 5T32DA01/63/-11. Danish Twin Registry is supported by the National Program for Research Infrastructure 2007 from the Danish Agency for Science, Technology and Innovation, The Research Council for Health and Disease, the Velux Foundation, and the US National Institute of Health (P01 AG08761). Netherlands Twin Register acknowledges the Netherlands Organization for Scientific Research (NWO) and MagW/ZonMW grants 904-61-090, 985-10-002, 912-10-020, 904-61-193,480-04-004, 463-06-001, 451-04-034, 400-05-717, Addiction-31160008, Middelgroot-911-09-032, and Spinozapremie 56-464-14192; VU University's Institute for Health and Care Research (EMGO+); and the European Research Council (ERC-230374), the Avera Institute, Sioux Falls, South Dakota (USA). Data collection and analyses in Finnish twin cohorts have been supported by ENGAGE-European Network for Genetic and Genomic Epidemiology, FP7-HEALTH-F4-2007, grant agreement number 201413, National Institute of Alcohol Abuse and Alcoholism (grants AA-12502, AA-00145, and AA-09203) to R J Rose, the Academy of Finland Center of Excellence in Complex Disease Genetics (grant numbers: 213506, 129680), and the Academy of Finland (grants 100499, 205585, 118555, 141054, 265240, 263278 and 264146 to J Kaprio). K Silventoinen is supported by Osaka University's International Joint Research Promotion Program. Since its origin the East Flanders Prospective Survey has been partly supported by grants from the Fund of Scientific Research, Flanders and Twins, a non-profit Association for Scientific Research in Multiple Births (Belgium). Waves 1-3 of Genesis 12-19 were funded by the W T Grant Foundation, the University of London Central Research fund and a Medical Research Council Training Fellowship (G81/343) and Career Development Award (G120/635) to Thalia C. Eley. Wave 4 was supported by grants from the Economic and Social Research Council (RES-00022-2206) and the Institute of Social Psychiatry (06/07-11) to Alice M. Gregory who was also supported at that time by a Leverhulme Research Fellowship (RF/2/RFG/2008/0145). Wave 5 was supported by funding to Alice M. Gregory from Goldsmiths, University of London. Anthropometric measurements of the Hungarian twins were supported by Medexpert Ltd., Budapest, Hungary. The Murcia Twin Registry is supported by Fundacion Seneca, Regional Agency for Science and Technology, Murcia, Spain (08633/PHCS/08, 15302/PHCS/10 & 19479/PI/14) and Ministry of Science and Innovation Spain (PSI2009-11560 & PSI2014-56680-R). The University of Southern California Twin Study is funded by a grant from the National Institute of Mental Health (R01 MH58354). South Korea Twin Registry is supported by National Research Foundation of Korea (NRF-371-2011-1 B0004/). S.Y. Oncel and F. Aliev are supported by Kirikkale University Research Grant: KKU, 2009/43 and TUBITAK grant 114C117. Washington State Twin Registry (formerly the University of Washington Twin Registry) was supported in part by grant NIH RC2 HL103416 (D. Buchwald,PI). The West Japan Twins and Higher Order Multiple Births Registry was supported by Grant-in-Aid for Scientific Research (B) (grant number 15H05105) from the Japan Society for the Promotion of Science.es_ES
dc.language.isoenges_ES
dc.publisherBiomed Centrales_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectprenatal hormone exposurees_ES
dc.subjectopposite-sex twinses_ES
dc.subjectheightes_ES
dc.subjectbody mass indexes_ES
dc.subjectCODATwinses_ES
dc.subjectpolycystic-ovary-syndromees_ES
dc.subjectrhesus-monkeyses_ES
dc.subjectfemale micees_ES
dc.subjectfetal sexes_ES
dc.subjectco-twinses_ES
dc.subjecttestosteronees_ES
dc.subjectdimorphismes_ES
dc.titleDoes the sex of one’s co-twin affect height and BMI in adulthood? A study of dizygotic adult twins from 31 cohortses_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holderThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.es_ES
dc.rights.holderAtribución 3.0 España*
dc.relation.publisherversionhttps://bsd.biomedcentral.com/articles/10.1186/s13293-017-0134-xes_ES
dc.identifier.doi10.1186/s13293-017-0134-x
dc.departamentoesFisiologíaes_ES
dc.departamentoesGenética, antropología física y fisiología animales_ES
dc.departamentoeuFisiologiaes_ES
dc.departamentoeuGenetika,antropologia fisikoa eta animalien fisiologiaes_ES


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This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Except where otherwise noted, this item's license is described as This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.