Show simple item record

dc.contributor.authorBen Salha, Ghada
dc.contributor.authorHerrera Díaz, René
dc.contributor.authorLengliz, Olfa
dc.contributor.authorAbderrabba, Manef
dc.contributor.authorLabidi Bouchrika, Jalel
dc.date.accessioned2020-01-16T10:11:27Z
dc.date.available2020-01-16T10:11:27Z
dc.date.issued2019-09-19
dc.identifier.citationMolecules 24(19) : (2019) // Article ID 3532es_ES
dc.identifier.issn1420-3049
dc.identifier.urihttp://hdl.handle.net/10810/38486
dc.description.abstractIn this study, Carum carvi L. essential oil (CEO) and Origanum majorana L. essential oil (MEO) was steam-distillated under reduced pressure. We henceforth obtained three fractions for each essential oil: CF1, CF2, CF3, MF1, MF2, and MF3. Then, these fractions were characterized using the gas chromatography-mass spectrometry (GC-MS) technique. The results indicated that some fractions were rich in oxygenated compounds (i.e., CF2, CF3, MF2, and MF3) with concentrations ranging from 79.21% to 98.56%. Therefore, the influence of the chemical composition of the essential oils on their antifungal activity was studied. For this purpose, three food spoilage fungi were isolated, identified, and inoculated in vitro, in order to measure the antifungal activity of CEO, MEO, and their fractions. The results showed that stronger fungi growth inhibitions (FGI) (above 95%) were found in fractions with higher percentages of oxygenated compounds, especially with (-)-carvone and terpin-4-ol as the major components. Firstly, this work reveals that the free-terpenes hydrocarbons fractions obtained from MEO present higher antifungal activity than the raw essential oil against two families of fungi. Then, it suggests that the isolation of (-)-carvone (97.15 +/- 5.97%) from CEO via vacuum distillation can be employed successfully to improve antifungal activity by killing fungi (FGI = 100%). This study highlights that separation under reduced pressure is a simple green method to obtain fractions or to isolate compounds with higher biological activity useful for pharmaceutical products or natural additives in formulations.es_ES
dc.description.sponsorshipThis research was funded by Basque Government (IT 1008-16 and POS-2018-1-0077)es_ES
dc.language.isoenges_ES
dc.publisherMDPIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.subjectcarum carvi Les_ES
dc.subjectoriganum majorana Les_ES
dc.subject(-)-carvonees_ES
dc.subjectterpin-4-oles_ES
dc.subjectantifungal activityes_ES
dc.subjectfree-terpenes hydrocarbonses_ES
dc.subjectL. essential oiles_ES
dc.subjectcarawayes_ES
dc.subjectfungies_ES
dc.subjectphytochemicalses_ES
dc.subjectcarvonees_ES
dc.subjectstoragees_ES
dc.subjectgrowthes_ES
dc.titleEffect of the Chemical Composition of Free-Terpene Hydrocarbons Essential Oils on Antifungal Activityes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holderThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0)es_ES
dc.rights.holderAtribución 3.0 España*
dc.relation.publisherversionhttps://www.mdpi.com/1420-3049/24/19/3532es_ES
dc.identifier.doi10.3390/molecules24193532
dc.departamentoesIngeniería química y del medio ambientees_ES
dc.departamentoeuIngeniaritza kimikoa eta ingurumenaren ingeniaritzaes_ES


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0)
Except where otherwise noted, this item's license is described as This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0)