Lignins from Agroindustrial by-Products as Natural Ingredients for Cosmetics: Chemical Structure and In Vitro Sunscreen and Cytotoxic Activities
dc.contributor.author | Gordobil Goñi, Oihana | |
dc.contributor.author | Olaizola Rebe, Paula | |
dc.contributor.author | Bañales Asurmendi, Jesús María | |
dc.contributor.author | Labidi Bouchrika, Jalel | |
dc.date.accessioned | 2020-03-25T18:45:14Z | |
dc.date.available | 2020-03-25T18:45:14Z | |
dc.date.issued | 2020-03-03 | |
dc.identifier.citation | Molecules 25(5) : (2020) // Article ID 1131 | es_ES |
dc.identifier.issn | 1420-3049 | |
dc.identifier.uri | http://hdl.handle.net/10810/42335 | |
dc.description.abstract | The growing concern about the environmental impact and human health risk related to the excessive use of synthetic ingredients in cosmetics and topical formulations calls for the exploration of safe and sustainable natural alternatives. Lignin-rich lignocellulosic industrial wastes such as hazelnut and walnut shells were used as a lignin polymer source. Agro-derived lignins were evaluated as a potential natural active ingredient for health care products. Aside from the structural characteristics of isolated lignins, which were identified by GPC, Py-GC–MS, and 2D HSQC NMR techniques, functional properties such as antioxidant power and UV absorption ability were investigated. The SPF values found for creams containing 5% of hazelnut and walnut lignin content were 6.9 and 4.5, respectively. Additionally, both lignin types presented appropriate protection against UVA radiation, highly interesting property to block the full ultraviolet spectrum. The biological activity of isolated lignins assessed at different concentrations (0.01–1 mg/mL) and different times (24, 48, and 72 h) on murine fibroblast cell line 3T3 suggested their suitability for cosmetic applications. | es_ES |
dc.description.sponsorship | The authors are grateful for the financial support received from the University of the Basque Country (post-doctoral grant of Ms. Gordobil DOCREC18/29) and from the Basque Government (doctoral grant of Ms. Olaizola PRE_2016_1_0269). | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | MDPI | es_ES |
dc.rights | info:eu-repo/semantics/openAccess | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by/3.0/es/ | |
dc.subject | hazelnut lignin | es_ES |
dc.subject | walnut lignin | es_ES |
dc.subject | monomeric composition | es_ES |
dc.subject | UV protection | es_ES |
dc.subject | antioxidant | es_ES |
dc.subject | cytotoxicity | es_ES |
dc.title | Lignins from Agroindustrial by-Products as Natural Ingredients for Cosmetics: Chemical Structure and In Vitro Sunscreen and Cytotoxic Activities | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.date.updated | 2020-03-13T13:10:01Z | |
dc.rights.holder | © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | es_ES |
dc.relation.publisherversion | https://www.mdpi.com/1420-3049/25/5/1131 | es_ES |
dc.identifier.doi | 10.3390/molecules25051131 | |
dc.departamentoes | Ingeniería química y del medio ambiente | |
dc.departamentoeu | Ingeniaritza kimikoa eta ingurumenaren ingeniaritza |
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Except where otherwise noted, this item's license is described as © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).