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dc.contributor.authorAmoruso, Lucia
dc.contributor.authorFinisguerra, Alessandra
dc.contributor.authorUrgesi, Cosimo
dc.date2020-11-26
dc.date.accessioned2020-06-16T13:45:41Z
dc.date.available2020-06-16T13:45:41Z
dc.date.issued2020
dc.identifier.citationSpatial frequency tuning of motor responses reveals differential contribution of dorsal and ventral systems to action comprehension Lucia Amoruso, Alessandra Finisguerra, Cosimo Urgesi Proceedings of the National Academy of Sciences Jun 2020, 117 (23) 13151-13161; DOI: 10.1073/pnas.1921512117es_ES
dc.identifier.issn0027-8424
dc.identifier.urihttp://hdl.handle.net/10810/43961
dc.descriptionfirst published May 26, 2020es_ES
dc.description.abstractUnderstanding object-directed actions performed by others is central to everyday life. This ability is thought to rely on the interaction between the dorsal action observation network (AON) and a ventral object recognition pathway. On this view, the AON would encode action kinematics, and the ventral pathway, the most likely intention afforded by the objects. However, experimental evidence supporting this model is still scarce. Here, we aimed to disentangle the contribution of dorsal vs. ventral pathways to action comprehension by exploiting their differential tuning to lowspatial frequencies (LSFs) and high-spatial frequencies (HSFs). We filtered naturalistic action images to contain only LSF or HSF and measured behavioral performance and corticospinal excitability (CSE) using transcranial magnetic stimulation (TMS). Actions were embedded in congruent or incongruent scenarios as defined by the compatibility between grips and intentions afforded by the contextual objects. Behaviorally, participants were better at discriminating congruent actions in intact than LSF images. This effect was reversed for incongruent actions, with better performance for LSF than intact and HSF. These modulations were mirrored at the neurophysiological level, with greater CSE facilitation for congruent than incongruent actions for HSF and the opposite pattern for LSF images. Finally, only for LSF did we observe CSE modulations according to grip kinematics. While results point to differential dorsal (LSF) and ventral (HSF) contributions to action comprehension for grip and context encoding, respectively, the negative congruency effect for LSF images suggests that object processing may influence action perception not only through ventral-to-dorsal connections, but also through a dorsal-to-dorsal route involved in predictive processing.es_ES
dc.description.sponsorshipThis work was supported by grants from the European Commission (MCSA-H2020-NBUCA; Grant 656881) (to L.A.), from the Italian Ministry of University and Research (PRIN 2017; Protocol 2017N7WCLP) (to C.U.), and from the Italian Ministry of Health (Ricerca Corrente 2020, Scientific Institute, IRCCS E. Medea) (to A.F.).es_ES
dc.language.isoenges_ES
dc.publisherProceedings of the National Academy of Sciences of the United States of Americaes_ES
dc.relationinfo:eu-repo/grantAgreement/EC/H2020-MSCA-NBUCA/656881es_ES
dc.rightsinfo:eu-repo/semantics/embargoedAccesses_ES
dc.subjectaction comprehensiones_ES
dc.subjectspatial frequencyes_ES
dc.subjectcontextes_ES
dc.subjecttranscranial magnetic stimulationes_ES
dc.titleSpatial frequency tuning of motor responses reveals differential contribution of dorsal and ventral systems to action comprehensiones_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.rights.holder© 2020 Published under the PNAS license.es_ES
dc.relation.publisherversionhttps://www.pnas.org/es_ES
dc.identifier.doi10.1073/pnas.1921512117


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